Class kappa-ell function - Revision history

en>Michael Hardy at 21:11, 26 June 2013

2013-06-26T21:11:16Z

← Older revision		Revision as of 23:11, 26 June 2013
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			''In vivo'', GD may also be estimated from equilibrium levels of T4 and T3. It is obtained with

			<math>\hat G_D = {{\beta _{31} (K_{M1} + [FT_4 ])(1 + K_{30} [TBG])[FT_3 ]} \over {\alpha _{31} [FT_4 ]}}</math>

			or

			<math>\hat G_D = {{\beta _{31} (K_{M1} + [FT_4 ])[TT_3 ]} \over {\alpha _{31} [FT_4 ]}}</math>

			<math>\alpha _{31}</math>: [[Dilution]] factor for T3 (reciprocal of apparent volume of distribution, 0.026 l<sup>−1</sup>)<br />
			<math>\beta _{31}</math>: [[Clearance (medicine)\|Clearance]] exponent for T3 (8e-6 sec<sup>−1</sup>)<br />
			''K''<sub>''M''1</sub>: [[Dissociation constant]] of type-1-deiodinase (5e-7 mol/l)<br />
			''K''<sub>30</sub>: Dissociation constant T3-TBG (2e9 l/mol)<ref name=dietrich2002>{{Cite book
			\|publisher = Logos-Verlag Berlin
			\|isbn = 978-3-89722-850-4
			\|publication-place = Berlin, Germany
			\|title = Der Hypophysen-Schilddrüsen-Regelkreis
			\|url = http://openlibrary.org/books/OL24586469M/Der_Hypophysen-Schilddrüsen-Regelkreis
			\|author = Dietrich, J. W.
			\|publication-date = 2002
			\|oclc = 50451543
			\|id = 3897228505
			\|postscript = <!-- Bot inserted parameter. Either remove it; or change its value to "." for the cite to end in a ".", as necessary. -->{{inconsistent citations}}
			}}</ref>

			{\| class="wikitable"
			\|'''Lower limit'''\|\|'''Upper limit'''\|\|'''Unit'''
			\|-
			\| 20<ref name=dietrich2002/> \|\| 40<ref name=dietrich2002/> \|\| nmol/s
			\|-
			\|}

			== Clinical significance ==
			GD correlates with [[body mass index]]<ref name=dietrich2002/><ref name="Liu2012">{{cite journal \| pmid = 22874844 \| title=Nonthyroidal Illness Syndrome: ist it Far Away From Crohn's Disease? \| year=2013 \| author=Liu S, Ren J, Zhao Y, Han G, Hong Z, Yan D, Chen J, Gu G, Wang G, Wang X, Fan C, Li J \| journal=J Clin Gastroenterol. \| volume = 47 \| issue = 2 \| pages = 153–9 \| doi = 10.1097/MCG.0b013e318254ea8a}}</ref><ref>Dietrich JW, Landgrafe, G, Fotiadou, EH. [http://www.hindawi.com/journals/jtr/2012/351864/ TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis] Journal of Thyroid Research, vol. 2012, Article ID 351864, 29 pages, 2012. [[doi:10.1155/2012/351864]]. PMID 23365787.</ref> and thyrotropin levels,<ref>Hoermann R, Midgley JE, Larisch R, Dietrich JW. Is pituitary TSH an adequate measure of thyroid hormone-controlled homoeostasis during thyroxine treatment? Eur J Endocrinol. 2013;168(2):271-80. [[doi:10.1530/EJE-12-0819]]. PMID 23184912.</ref> and it is reduced in [[Euthyroid sick syndrome\|nonthyroidal illness]] with hypodeiodination.<ref name=Rosolowska-Huszcz2005>{{cite journal \| pmid = 16230785 \| volume=27 \| issue=3 \| title=Influence of low protein diet on nonthyroidal illness syndrome in chronic renal failure \| year=2005 \| month=August \| author=Rosolowska-Huszcz D, Kozlowska L, Rydzewski A \| journal=Endocrine \| pages=283–8 \| doi=10.1385/ENDO:27:3:283}}</ref><ref name=Liu2012 /><ref>Han G, Ren J, Liu S, Gu G, Ren H, Yan D, Chen J, Wang G, Zhou B, Wu X, Yuan Y, Li J. Nonthyroidal illness syndrome in enterocutaneous fistulas. Am J Surg. 2013 Sep;206(3):386-92 [[doi:10.1016/j.amjsurg.2012.12.011]]. PMID 23809674.</ref>

			==See also==
			* [[Thyroid function tests]]
			* [[Thyroid's secretory capacity]]

			== External links ==
			* [http://spina.sf.net SPINA Thyr: Open source software for calculating GT and GD]

			==References==
			{{reflist}}

			[[Category:Chemical pathology]]
			[[Category:Blood tests]]
			[[Category:Endocrine procedures]]
			[[Category:Thyroidological methods]]

en>Berek: added Category:Control theory using HotCat

2012-01-16T11:34:42Z

added Category:Control theory using HotCat

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