View source for 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

{{enzyme
| Name = beta-diketone hydrolase
| EC_number = 3.7.1.7
| CAS_number = 97955-12-9
| IUBMB_EC_number = 3/7/1/7
| GO_code = 0047699
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''beta-diketone hydrolase''' ({{EC number|3.7.1.7}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:nonane-4,6-dione + H<sub>2</sub>O <math>\rightleftharpoons</math> pentan-2-one + butanoate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[nonane-4,6-dione]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[2-pentanone]] and [[butanoate]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on carbon-carbon bonds in ketonic substances.  The systematic name of this enzyme class is '''nonane-4,6-dione acylhydrolase'''. This enzyme is also called '''oxidized PVA hydrolase'''.  

==Structural studies==

As of late 2007, two [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|2J5G}} and {{PDB link|2J5S}}.

==References==
{{reflist|1}}
* {{cite journal | author = Sakai K, Hamada N and Watanabe Y | date = 1983 | title = Separation of secondary alcohol oxidase and oxidized poly(vinyl alcohol) hydrolase by hydrophobic and dye-ligand chromatographies | journal = Agric. Biol. Chem.  | volume = 47 | pages = 153&ndash;155 | doi = 10.1271/bbb1961.47.153 }}
* {{cite journal | author = Sakai K, Hamada N and Watanabe Y | date = 1985 | title = A new enzyme, beta-diketone hydrolase: a component of a poly(vinyl alcohol)-degrading enzyme preparation | journal = Agric. Biol. Chem.  | volume = 49 | pages = 1901&ndash;1902 | doi = 10.1271/bbb1961.49.1901 | issue = 6 }}

{{hydrolase-stub}}

[[Category:EC 3.7.1]]
[[Category:Enzymes of known structure]]