View source for (myelin-proteolipid) O-palmitoyltransferase

{{enzyme
| Name = phloroisovalerophenone synthase
| EC_number = 2.3.1.156
| CAS_number = 
| IUBMB_EC_number = 2/3/1/156
| GO_code = 0050634
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''phloroisovalerophenone synthase''' ({{EC number|2.3.1.156}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:isovaleryl-CoA + 3 malonyl-CoA <math>\rightleftharpoons</math> 4 CoASH + 3 CO<sub>2</sub> + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[isovaleryl-CoA]] and [[malonyl-CoA]], whereas its 3 [[product (chemistry)|products]] are [[CoASH]], [[carbon dioxide|CO<sub>2</sub>]], and [[3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one]].

This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups.  The systematic name of this enzyme class is '''isovaleryl-CoA:malonyl-CoA acyltransferase'''. Other names in common use include '''valerophenone synthase''', and '''3-methyl-1-(trihydroxyphenyl)butan-1-one synthase'''.  

==References==
{{reflist|1}}
* {{cite journal | author = Verpoorte R | date = 1997 | title = Enzymes from the biosynthesis of hop alpha and beta acids | journal = Proc. 26th Congr. Eur. Brew.  | volume = Conv. | pages = 215&ndash;221 }}
* {{cite journal | author = G, Verpoorte R and Schroder J | date = 1998 | title = 4-Hydroxy-2-pyrone formation by chalcone and stilbene synthase with nonphysiological substrates | journal = [[Phytochemistry (journal)|Phytochemistry]]  | volume = 49 | pages = 1945&ndash;1951 | doi = 10.1016/S0031-9422(98)00346-X | pmid=9883590 | issue = 7}}

[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]

{{transferase-stub}}