View source for 2,3-bisphosphoglycerate 3-phosphatase

{{Infobox enzyme
| Name = N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
| EC_number = 3.1.4.54
| CAS_number = 
| IUBMB_EC_number = 3/1/4/54
| GO_code = 
| image = 
| width = 
| caption =
}}
'''N-acetylphosphatidylethanolamine-hydrolysing phospholipase D''' ({{EC number|3.1.4.54}}, ''NAPE-PLD'', ''anandamide-generating phospholipase D'', ''N-acyl phosphatidylethanolamine phospholipase D'', ''NAPE-hydrolyzing phospholipase D'') is an [[enzyme]] with system name ''N-acetylphosphatidylethanolamine phosphatidohydrolase''.<ref>{{cite journal | title = Molecular characterization of a phospholipase D generating anandamide and its congeners |author = Okamoto, Y., Morishita, J., Tsuboi, K., Tonai, T. and Ueda, N. |journal = J. Biol. Chem. |date = 2004 |volume = 279 |pages = 5298–5305 |pmid = 14634025 | doi = 10.1074/jbc.M306642200 | issue = 7}}</ref><ref>{{cite journal | title = Functional analysis of the purified anandamide-generating phospholipase D as a member of the metallo-&beta;-lactamase family |author = Wang, J., Okamoto, Y., Morishita, J., Tsuboi, K., Miyatake, A. and Ueda, N. |journal = J. Biol. Chem. |date = 2006 |volume = 281 |pages = 12325–12335 |pmid = 16527816 | doi = 10.1074/jbc.M512359200 | issue = 18}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: N-acylphosphatidylethanolamine + H<sub>2</sub>O <math>\rightleftharpoons</math> [[N-acylethanolamine]] + a 1,2-diacylglycerol 3-phosphate

This enzyme is involved in the [[biosynthesis]] of [[anandamide]]. 

== References ==
{{reflist}}

== External links ==
* {{MeshName|N-acetylphosphatidylethanolamine-hydrolysing+phospholipase+D}}

[[Category:EC 3.1.4]]