View source for 2-acylglycerol O-acyltransferase

{{enzyme
| Name = 3-oxoadipyl-CoA thiolase
| EC_number = 2.3.1.174
| CAS_number = 
| IUBMB_EC_number = 2/3/1/174
| GO_code = 
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''3-oxoadipyl-CoA thiolase''' ({{EC number|2.3.1.174}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:succinyl-CoA + acetyl-CoA <math>\rightleftharpoons</math> CoA + 3-oxoadipyl-CoA

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[succinyl-CoA]] and [[acetyl-CoA]], whereas its two [[product (chemistry)|products]] are [[coenzyme A|CoA]] and [[3-oxoadipyl-CoA]].

This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups.  The systematic name of this enzyme class is '''succinyl-CoA:acetyl-CoA C-succinyltransferase'''. This enzyme participates in [[benzoate degradation via hydroxylation]].  

3-Oxoadipyl-CoA thiolase belongs to the [[thiolase]] family of enzymes.

==References==
{{reflist|1}}
* {{cite journal | author = Kaschabek SR, Kuhn B, Muller D, Schmidt E, Reineke W | date = 2002 | title = Degradation of Aromatics and Chloroaromatics by Pseudomonas sp. Strain B13: Purification and Characterization of 3-Oxoadipate:Succinyl-Coenzyme A (CoA) Transferase and 3-Oxoadipyl-CoA Thiolase | journal = J. Bacteriol.  | volume = 184 | pages = 207&ndash;15  | pmid = 11741862 | doi = 10.1128/JB.184.1.207-215.2002 | issue = 1 | pmc = 134768 }}
* {{cite journal | author = Gobel M, Kassel-Cati K, Schmidt E, Reineke W | date = 2002 | title = Degradation of Aromatics and Chloroaromatics by Pseudomonas sp. Strain B13: Cloning, Characterization, and Analysis of Sequences Encoding 3-Oxoadipate:Succinyl-Coenzyme A (CoA) Transferase and 3-Oxoadipyl-CoA Thiolase | journal = J. Bacteriol.  | volume = 184 | pages = 216&ndash;23  | pmid = 11741863 | doi = 10.1128/JB.184.1.216-223.2002 | issue = 1 | pmc = 134769 }}

{{transferase-stub}}

[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]