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{{enzyme
| Name = 4-hydroxyproline epimerase
| EC_number = 5.1.1.8
| CAS_number = 9024-23-1
| IUBMB_EC_number = 5/1/1/8
| GO_code = 0047580
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''4-hydroxyproline epimerase''' ({{EC number|5.1.1.8}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:trans-4-hydroxy-L-proline <math>\rightleftharpoons</math> cis-4-hydroxy-D-proline

Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[trans-4-hydroxy-L-proline]], and one [[product (chemistry)|product]], [[cis-4-hydroxy-D-proline]].

This enzyme belongs to the family of [[isomerase]]s, specifically those [[racemase]]s and [[epimerase]]s acting on [[amino acid]]s and derivatives.  The systematic name of this enzyme class is '''4-hydroxyproline 2-epimerase'''. Other names in common use include '''hydroxyproline epimerase''', '''hydroxyproline 2-epimerase''', and '''L-hydroxyproline epimerase'''.  This enzyme participates in [[arginine and proline metabolism]].

==References==
{{reflist|1}}
* {{cite journal | author = Adams E and Norton IL | year = 1964 | title = Purification and properties of inducible hydroxyproline 2-epimerase from Pseudomonas | journal = J. Biol. Chem.  | volume = 239 | pages = 1525&ndash;1535 | pmid=14189888}}

[[Category:EC 5.1.1]]
[[Category:Enzymes of unknown structure]]


{{isomerase-stub}}