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{{enzyme
| Name = 3-oxo-5-beta-steroid 4-dehydrogenase
| EC_number = 1.3.99.6
| CAS_number = 9067-97-4
| IUBMB_EC_number = 1/3/99/6
| GO_code = 0047568
| image =
| width =
| caption =
}}
{{orphan|date=December 2008}}
In [[enzymology]], a '''3-oxo-5beta-steroid 4-dehydrogenase''' ({{EC number|1.3.99.6}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:a 3-oxo-5beta-steroid + acceptor <math>\rightleftharpoons</math> a 3-oxo-Delta<sub>4</sub>-steroid + reduced acceptor

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3-oxo-5beta-steroid]] and [[Electron acceptor|acceptor]], whereas its two [[product (chemistry)|products]] are [[3-oxo-Delta4-steroid]] and [[reduced acceptor]].

This enzyme belongs to the family of [[oxidoreductase]]s, to be specific, those acting on the CH-CH group of donor with other acceptors.  The systematic name of this enzyme class is '''3-oxo-5beta-steroid:acceptor Delta4-oxidoreductase'''. This enzyme is also called '''3-oxo-5beta-steroid:(acceptor) Delta4-oxidoreductase'''.  This enzyme participates in 3 [[metabolism|metabolic pathways]]: [[bile acid biosynthesis]], [[c21-steroid hormone metabolism]], and [[androgen and estrogen metabolism]].

==References==
{{reflist|1}}
* {{cite journal | author = Davidson SJ, Talalay P | year = 1966 | title = Purification and mechanism of action of a steroid delta-4-5-beta-dehydrogenase | journal = J. Biol. Chem.  | volume = 241 | pages = 906&ndash;15  | pmid = 5907467 | issue = 4 }}

[[Category:EC 1.3.99]]
[[Category:Enzymes of unknown structure]]


{{1.3-enzyme-stub}}