View source for 23S rRNA (pseudouridine1915-N3)-methyltransferase

{{Infobox enzyme
| Name = 23S rRNA (uracil<sup>747</sup>-C<sup>5</sup>)-methyltransferase
| EC_number = 2.1.1.189
| CAS_number = 
| IUBMB_EC_number = 2/1/1/189
| GO_code = 
| image = 
| width = 
| caption =
}}
'''23S rRNA (uracil<sup>747</sup>-C<sup>5</sup>)-methyltransferase''' ({{EC number|2.1.1.189}}, ''YbjF'', ''RumB'', ''RNA uridine methyltransferase B'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:23S rRNA (uracil<sup>747</sup>-C<sup>5</sup>)-methyltransferase''.<ref>{{cite journal | title = Identifying the methyltransferases for m<sup>5</sup>U<sup>747</sup> and m<sup>5</sup>U<sup>1939</sup> in 23S rRNA using MALDI mass spectrometry |author = Madsen, C.T., Mengel-Jorgensen, J., Kirpekar, F. and Douthwaite, S. |journal = Nucleic Acids Res. |year = 2003 |volume = 31 |pages = 4738–4746 |pmid = 12907714}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[S-adenosyl-L-methionine]] + [[uracil]]<sup>747</sup> in [[Ribosomal RNA|23S rRNA]] <math>\rightleftharpoons</math> [[S-adenosyl-L-homocysteine]] + [[5-methyluracil]]<sup>747</sup> in 23S rRNA

The enzyme specifically methylates uracil<sup>747</sup> at C<sup>5</sup> in 23S rRNA.

== References ==
{{reflist}}

== External links ==
* {{MeshName|23S+rRNA+(uracil747-C5)-methyltransferase}}

[[Category:EC 2.1.1]]