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{{enzyme
| Name = 4-phytase
| EC_number = 3.1.3.26
| CAS_number = 9001-89-2
| IUBMB_EC_number = 3/1/3/26
| GO_code = 0008707
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''4-phytase''' ({{EC number|3.1.3.26}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:myo-inositol hexakisphosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[myo-inositol hexakisphosphate]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[1D-myo-inositol 1,2,3,4,5-pentakisphosphate]] and [[phosphate]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on phosphoric [[ester|monoester]] bonds.  The systematic name of this enzyme class is '''myo-inositol-hexakisphosphate 6-phosphohydrolase'''. Other names in common use include '''6-phytase (name based on 1L-numbering system and not 1D-numbering)''', '''phytase''', and '''phytate 6-phosphatase'''.  This enzyme participates in [[inositol phosphate metabolism]].  

==References==
{{reflist|1}}
* {{cite journal | author = Johnson LF, Tate ME | date = 1969 | title = The structure of myo-inositol pentaphosphates | journal = Ann. N. Y. Acad. Sci.  | volume = 165 | pages = 526&ndash;32  | pmid = 4310376 | issue = 2 |doi=10.1111/j.1749-6632.1970.tb56420.x}}
* {{cite journal | author = Tomlinson RV and Ballou CE | date = 1962 | title = Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase | journal = Biochemistry  | volume = 1 | pages = 166&ndash;171 | doi = 10.1021/bi00907a025 | pmid = 13921788 }}
* {{cite journal | author = Lim PE, Tate ME | date = 1973 | title = The phytases. II. Properties of phytase fractions F 1  and F 2  from wheat bran and the myoinositol phosphates produced by fraction F 2  | journal = Biochim. Biophys. Acta.  | volume = 302 | pages = 316&ndash;28  | pmid = 4349266 | issue = 2 }}
* {{cite journal | author = Cosgrove DJ | date =  | title = Inositol Phosphates: Their Chemistry, Biochemistry, and Physiology, Elsevier, Amsterdam, 1980 | journal =  | volume =  | pages =  }}

{{hydrolase-stub}}

[[Category:EC 3.1.3]]
[[Category:Enzymes of unknown structure]]