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{{enzyme
| Name = Ectoine synthase
| EC_number = 4.2.1.108
| CAS_number = 
| IUBMB_EC_number = 4/2/1/108
| GO_code = 
| image = 
| width = 
| caption = 
}}

In [[enzymology]], an '''ectoine synthase''' ({{EC number|4.2.1.108}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:N<sub>4</sub>-acetyl-L-2,4-diaminobutanoate <math>\rightleftharpoons</math> L-ectoine + H<sub>2</sub>O

Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[N4-acetyl-L-2,4-diaminobutanoate]], and two [[product (chemistry)|products]], [[ectoine|L-ectoine]] and [[water|H<sub>2</sub>O]].

This enzyme belongs to the family of [[lyase]]s, specifically the hydro-lyases, which cleave carbon-oxygen bonds.  The systematic name of this enzyme class is '''N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming)'''. Other names in common use include '''N-acetyldiaminobutyrate dehydratase''', '''N-acetyldiaminobutanoate dehydratase''', '''L-ectoine synthase''', '''EctC''', and '''4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming)'''.  This enzyme participates in [[glycine, serine and threonine metabolism]].  

==References==
{{reflist|1}}
* {{cite journal | author = Peters P, Galinski EA and Truper HG | date = 1990 | title = The biosynthesis of ectoine | journal = FEMS Microbiol. Lett.  | volume = 71 | pages = 157&ndash;162 | doi = 10.1111/j.1574-6968.1990.tb03815.x }}
* {{cite journal | author = A, Takano M, Murooka Y | date = 1999 | title = Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata | journal = J. Bacteriol.  | volume = 181 | pages = 91&ndash;9  | pmid = 9864317 | issue = 1 | pmc = 103536 }}
* {{cite journal | author = Kuhlmann AU, Bremer E | date = 2002 | title = Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp | journal = Appl. Environ. Microbiol.  | volume = 68 | pages = 772&ndash;83  | pmid = 11823218 | doi = 10.1128/AEM.68.2.772-783.2002 | issue = 2 | pmc = 126723 }}
* {{cite journal | author = Louis P, Galinski EA | date =  Pt 4 | title = Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli | journal = Microbiology.  | volume = 143 | pages = 1141&ndash;9  | pmid = 9141677 | doi = 10.1099/00221287-143-4-1141 | issue = 4 }}

{{4.2-enzyme-stub}}

[[Category:EC 4.2.1]]
[[Category:Enzymes of unknown structure]]