View source for DTMP kinase

{{enzyme
| Name = fucokinase
| EC_number = 2.7.1.52
| CAS_number = 37278-00-5
| IUBMB_EC_number = 2/7/1/52
| GO_code = 0050201
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''fucokinase''' ({{EC number|2.7.1.52}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:ATP + L-fucose <math>\rightleftharpoons</math> ADP + beta-L-fucose 1-phosphate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[L-fucose]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[beta-L-fucose 1-phosphate]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring phosphorus-containing groups ([[phosphotransferase]]s) with an alcohol group as acceptor.  The systematic name of this enzyme class is '''ATP:beta-L-fucose 1-phosphotransferase'''. Other names in common use include '''fucokinase (phosphorylating)''', '''fucose kinase''', '''L-fucose kinase''', '''L-fucokinase''', '''ATP:6-deoxy-L-galactose 1-phosphotransferase''', and '''ATP:L-fucose 1-phosphotransferase'''. Fucokinase is commonly abbreviated as '''fuc-K'''.  This enzyme participates in [[Fructose metabolism|fructose]] and [[Mannose metabolism|mannose metabolism]].  

==References==
{{reflist|1}}
* {{cite journal | author = Ishihara H, Massaro DJ, Heath EC | date = 1968 | title = The metabolism of L-fucose. 3. The enzymatic synthesis of beta-L-fucose 1-phosphate | journal = J. Biol. Chem.  | volume = 243 | pages = 1103&ndash;9  | pmid = 5646161 | issue = 6 }}
* {{cite journal | author = Butler W, Serif GS | date = 1985 | title = Fucokinase, its anomeric specificity and mechanism of phosphate group transfer | journal = Biochim. Biophys. Acta.  | volume = 829 | pages = 238&ndash;43  | pmid = 2986701 | issue = 2 | doi = 10.1016/0167-4838(85)90193-1 }}
* {{cite journal | author = Park SH, Pastuszak I, Drake R, Elbein AD | date = 1998 | title = Purification to apparent homogeneity and properties of pig kidney L-fucose kinase | journal = J. Biol. Chem.  | volume = 273 | pages = 5685&ndash;91  | pmid = 9488699 | doi = 10.1074/jbc.273.10.5685 | issue = 10 }}

{{enzyme-stub}}

[[Category:EC 2.7.1]]
[[Category:Enzymes of unknown structure]]