View source for Dolichylphosphate-mannose phosphodiesterase

{{enzyme
| Name = glucose-1-phosphatase
| EC_number = 3.1.3.10
| CAS_number = 9001-38-1
| IUBMB_EC_number = 3/1/3/10
| GO_code = 0008877
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''glucose-1-phosphatase''' ({{EC number|3.1.3.10}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:alpha-D-glucose 1-phosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> D-glucose + phosphate

Thus, the two [[substrate (biochemistry)|substrates]] of this [[enzyme]] are [[alpha-D-glucose 1-phosphate]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[D-glucose]] and [[phosphate]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on phosphoric [[ester|monoester]] bonds.  The systematic name of this enzyme class is '''alpha-D-glucose-1-phosphate phosphohydrolase'''. This enzyme participates in [[glycolysis / gluconeogenesis]].

==Structural studies==

As of late 2007, only one [[tertiary structure|structure]] has been solved for this class of enzymes, with the [[Protein Data Bank|PDB]] accession code {{PDB link|1NT4}}.

==References==
{{reflist|1}}
* {{cite journal | author = FAULKNER P | year = 1955 | title = A hexose-1-phosphatase in silkworm blood | journal = Biochem. J.  | volume = 60 | pages = 590&ndash;6  | pmid = 13249953 | issue = 4 | pmc = 1216157 }}
* {{cite journal | author = Turner DH and Turner JF | year = 1960 | title = The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds | journal = Biochem. J.  | volume = 74 | pages = 486&ndash;491 | pmid=13839934 | pmc = 1204246 | issue = 3}}

[[Category:EC 3.1.3]]
[[Category:Enzymes of known structure]]


{{hydrolase-stub}}