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{{Infobox enzyme
| Name = UDP-4-amino-4-deoxy-L-arabinose formyltransferase
| EC_number = 2.1.2.13
| CAS_number = 
| IUBMB_EC_number = 2/1/2/13
| GO_code = 
| image = 
| width = 
| caption =
}}
'''UDP-4-amino-4-deoxy-L-arabinose formyltransferase''' ({{EC number|2.1.2.13}}, ''UDP-L-Ara4N formyltransferase'', ''ArnAFT'') is an [[enzyme]] with system name ''10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase''.<ref>{{cite journal | title = A formyltransferase required for polymyxin resistance in <em>Escherichia coli</em> and the modification of lipid A with 4-amino-4-deoxy-<small>L</small>-arabinose.  Identification and function of UDP-4-deoxy-4-formamido-<small>L</small>-arabinose |author = Breazeale, S.D., Ribeiro, A.A., McClerren, A.L. and Raetz, C.R.H. |journal = J. Biol. Chem. |date = 2005 |volume = 280 |pages = 14154-14167 |pmid = 15695810 |doi=10.1074/jbc.M414265200}}</ref><ref>{{cite journal | title = Crystal structure and mechanism of the <em>Escherichia coli</em> ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with  4-amino-4-deoxy-<small>L</small>-arabinose and polymyxin resistance |author = Gatzeva-Topalova, P.Z., May, A.P. and Sousa, M.C. |journal = Biochemistry |date = 2005 |volume = 44 |pages = 5328-5338 |pmid = 15807526 |doi=10.1021/bi047384g |issue=14}}</ref><ref>{{cite journal | title = Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in  4-amino-4-deoxy-<small>L</small>-arabinose biosynthesis |author = Williams, G.J., Breazeale, S.D., Raetz, C.R.H. and Naismith, J.H. |journal = J. Biol. Chem. |date = 2005 |volume = 280 |pages = 23000-23008 |pmid = 15809294 |doi=10.1074/jbc.M501534200 |pmc=3326539}}</ref><ref>{{cite journal | title = Structure and mechanism of ArnA: conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance |author = Gatzeva-Topalova, P.Z., May, A.P. and Sousa, M.C. |journal = Structure |date = 2005 |volume = 13 |pages = 929-942 |pmid = 15939024 |doi=10.1016/j.str.2005.03.018 |pmc=2997725}}</ref><ref>{{cite journal | title = An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in <em>Escherichia coli</em> |author = Yan, A., Guan, Z. and Raetz, C.R.H. |journal = J. Biol. Chem. |date = 2007 |volume = 282 |pages = 36077-36089 |pmid = 17928292 |doi=10.1074/jbc.M706172200 |pmc=2613183}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[10-formyltetrahydrofolate]] + UDP-4-amino-4-deoxy-beta-L-arabinopyranose <math>\rightleftharpoons</math> [[5,6,7,8-tetrahydrofolate]] + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose

The activity is part of a bifunctional enzyme that also performs the [[EC 1.1.1.305]] reaction .

== References ==
{{reflist}}

== External links ==
* {{MeshName|UDP-4-amino-4-deoxy-L-arabinose+formyltransferase}}

[[Category:EC 2.1.2]]