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{{Infobox enzyme
| Name = Spermine oxidase
| EC_number = 1.5.3.16
| CAS_number = 
| IUBMB_EC_number = 1/5/3/16
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Spermine oxidase''' ({{EC number|1.5.3.16}}, ''PAOh1/SMO'', ''AtPAO1'', ''AtPAO4'', ''SMO'') is an [[enzyme]] with system name ''spermidine:oxygen oxidoreductase (spermidine-forming)''.<ref>{{cite journal | title = Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology |author = Murray-Stewart, T., Wang, Y., Goodwin, A., Hacker, A., Meeker, A. and Casero, R.A., Jr. |journal = FEBS J. |year = 2008 |volume = 275 |pages = 2795–2806 |pmid = 18422650 |doi=10.1111/j.1742-4658.2008.06419.x |issue=11}}</ref><ref>{{cite journal | title = Heterologous expression and characterization of mouse spermine oxidase |author = Cervelli, M., Polticelli, F., Federico, R. and Mariottini, P. |journal = J. Biol. Chem. |year = 2003 |volume = 278 |pages = 5271–5276 |pmid = 12458219 |doi=10.1074/jbc.M207888200}}</ref><ref>{{cite journal | title = Heterologous expression and biochemical characterization of a polyamine oxidase from <em>Arabidopsis</em> involved in polyamine back conversion |author = Tavladoraki, P., Rossi, M.N., Saccuti, G., Perez-Amador, M.A., Polticelli, F., Angelini, R. and Federico, R. |journal = Plant Physiol. |year = 2006 |volume = 141 |pages = 1519–1532 |pmid = 16778015 |doi=10.1104/pp.106.080911 |issue=4 |pmc=1533960}}</ref><ref>{{cite journal | title = Properties of purified recombinant human polyamine oxidase, PAOh1/SMO |author = Wang, Y., Murray-Stewart, T., Devereux, W., Hacker, A., Frydman, B., Woster, P.M. and Casero, R.A., Jr. |journal = Biochem. Biophys. Res. Commun. |year = 2003 |volume = 304 |pages = 605–611 |pmid = 12727196 |doi=10.1016/S0006-291X(03)00636-3}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[spermine]] + O<sub>2</sub> + H<sub>2</sub>O <math>\rightleftharpoons</math> [[spermidine]] + 3-aminopropanal + H<sub>2</sub>O<sub>2</sub>

The enzyme from ''[[Arabidopsis thaliana]]'' oxidizes [[norspermine]] to [[norspermidine]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|Spermine+oxidase}}

[[Category:EC 1.5.3]]