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{{Infobox enzyme
| Name = 16S rRNA pseudouridine<sup>516</sup> synthase
| EC_number = 5.4.99.19
| CAS_number = 
| IUBMB_EC_number = 5/4/99/19
| GO_code = 
| image = 
| width = 
| caption =
}}
'''16S rRNA pseudouridine<sup>516</sup> synthase''' ({{EC number|5.4.99.19}}, ''16S RNA pseudouridine<sup>516</sup> synthase'', ''16S PsiI<sup>516</sup> synthase'', ''16S RNA Psi<sup>516</sup> synthase'', ''RNA pseudouridine synthase RsuA'', ''RsuA'', ''16S RNA pseudouridine 516 synthase'') is an [[enzyme]] with system name ''16S rRNA-uridine<sup>516</sup> uracil mutase''.<ref>{{cite journal | title = Purification, cloning, and properties of the 16''S'' RNA pseudouridine 516 synthase from ''Escherichia coli'' |author = Wrzesinski, J., Bakin, A., Nurse, K., Lane, B.G. and Ofengand, J. |journal = Biochemistry |year = 1995 |volume = 34 |pages = 8904–8913 |pmid = 7612632}}</ref><ref>{{cite journal | title = 16S ribosomal RNA pseudouridine synthase RsuA of ''Escherichia coli'': deletion, mutation of the conserved Asp<sup>102</sup> residue, and sequence  comparison among all other pseudouridine synthases |author = Conrad, J., Niu, L., Rudd, K., Lane, B.G. and Ofengand, J. |journal = RNA |year = 1999 |volume = 5 |pages = 751–763 |pmid = 10376875}}</ref><ref>{{cite journal | title = Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP |author = Sivaraman, J., Sauve, V., Larocque, R., Stura, E.A., Schrag, J.D., Cygler, M. and Matte, A. |journal = Nat. Struct. Biol. |year = 2002 |volume = 9 |pages = 353–358 |pmid = 11953756}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: 16S rRNA uridine<sup>516</sup> <math>\rightleftharpoons</math> 16S rRNA pseudouridine<sup>516</sup>

The enzyme is specific for uridine<sup>516</sup> in 16S rRNA.

== References ==
{{reflist}}

== External links ==
* {{MeshName|16S+rRNA+pseudouridine516+synthase}}

[[Category:EC 5.4.99]]