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{{enzyme
| Name = 3-chloro-D-alanine dehydrochlorinase
| EC_number = 4.5.1.2
| CAS_number = 78990-65-5
| IUBMB_EC_number = 4/5/1/2
| GO_code = 0019149
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''3-chloro-D-alanine dehydrochlorinase''' ({{EC number|4.5.1.2}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:3-chloro-D-alanine + H<sub>2</sub>O <math>\rightleftharpoons</math> pyruvate + chloride + NH<sub>3</sub>

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3-chloro-D-alanine]] and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[pyruvate]], [[chloride]], and [[ammonia|NH<sub>3</sub>]].

This enzyme belongs to the family of [[lyase]]s, specifically the class of carbon-halide lyases.  The systematic name of this enzyme class is '''3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)'''. Other names in common use include '''beta-chloro-D-alanine dehydrochlorinase''', and '''3-chloro-D-alanine chloride-lyase (deaminating)'''.  It employs one [[cofactor (biochemistry)|cofactor]], [[pyridoxal phosphate]].

==References==
{{reflist|1}}
* {{cite journal | author = Nagasawa T, Ishii T, Yamada H | year = 1988 | title = Physiological comparison of D-cysteine desulfhydrase of Escherichia coli with 3-chloro-D-alanine dehydrochlorinase of Pseudomonas putida CR 1-1 | journal = Arch. Microbiol.  | volume = 149 | pages = 413&ndash;6  | pmid = 3132906 | doi = 10.1007/BF00425580 | issue = 5 }}
* {{cite journal | author = Yamada H, Nagasawa T, Ohkishi H, Kawakami B, Tani Y | year = 1981 | title = Synthesis of D-cysteine from 3-chloro-D-alanine and hydrogen sulfide by 3-chloro-D-alanine hydrogen chloride-lyase (deaminating) of Pseudomonas putida | journal = Biochem. Biophys. Res. Commun.  | volume = 100 | pages = 1104&ndash;10  | pmid = 6791643 | doi = 10.1016/0006-291X(81)91937-9 | issue = 3 }}

[[Category:EC 4.5.1]]
[[Category:Pyridoxal phosphate enzymes]]
[[Category:Enzymes of unknown structure]]


{{lyase-stub}}