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{{enzyme
| Name = phenylalanine 2-monooxygenase
| EC_number = 1.13.12.9
| CAS_number = 84012-76-0
| IUBMB_EC_number = 1/13/12/9
| GO_code = 0050172
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''phenylalanine 2-monooxygenase''' ({{EC number|1.13.12.9}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:L-phenylalanine + O<sub>2</sub> <math>\rightleftharpoons</math> 2-phenylacetamide + CO<sub>2</sub> + H<sub>2</sub>O

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[L-phenylalanine]] and [[oxygen|O<sub>2</sub>]], whereas its 3 [[product (chemistry)|products]] are [[2-phenylacetamide]], [[carbon dioxide|CO<sub>2</sub>]], and [[water|H<sub>2</sub>O]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on single donors with O<sub>2</sub> as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen (internal monooxygenases o internal mixed-function oxidases).  The systematic name of this enzyme class is '''L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)'''. Other names in common use include '''L-phenylalanine oxidase (deaminating and decarboxylating)''', and '''phenylalanine (deaminating, decarboxylating)oxidase'''.  This enzyme participates in [[phenylalanine metabolism]].  

==References==
{{reflist|1}}
* {{cite journal | author = Koyama H | date = Tokyo | title = Purification and characterization of a novel L-phenylalanine oxidase (Deaminating and decarboxylating) from Pseudomonas sp. P-501 | journal = J.  | volume = Biochem. | pages = 1235&ndash;40  | pmid = 7174643 | issue = 4 }}
* {{cite journal | author = Koyama H | date = Tokyo | title = Oxidation and oxygenation of L-amino acids catalyzed by a L-phenylalanine oxidase (deaminating and decarboxylating) from Pseudomonas sp. P-501 | journal = J.  | volume = Biochem. | pages = 421&ndash;7  | pmid = 6501250 | issue = 2 }}
* {{cite journal | author = Koyama H | date = 1984 | title = A simple and rapid enzymatic determination of L-phenylalanine with a novel L-phenylalanine oxidase (deaminating and decarboxylating) from Pseudomonas sp. P-501 | journal = Clin. Chim. Acta.  | volume = 136 | pages = 131&ndash;6  | pmid = 6692570 | doi = 10.1016/0009-8981(84)90284-5 | issue = 2–3 }}
* {{cite journal | author = Koyama H, Suzuki H | date = Tokyo | title = Spectral and kinetic studies on Pseudomonas L-phenylalanine oxidase (deaminating and decarboxylating) | journal = J.  | volume = Biochem. | pages = 859&ndash;66  | pmid = 3818566 | issue = 4 }}

{{1.13-enzyme-stub}}

[[Category:EC 1.13.12]]
[[Category:Enzymes of unknown structure]]