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{{Infobox enzyme
| Name = Nucleoside oxidase
| EC_number = 1.1.3.28
| CAS_number = 82599-71-1
| IUBMB_EC_number = 1/1/3/28
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Nucleoside oxidase''' ({{EC number|1.1.3.28}}) is an [[enzyme]] with system name ''nucleoside:oxygen 5'-oxidoreductase''.<ref>{{cite journal | title = Purification and reaction of a new enzyme, nucleoside oxidase |author = Isono, Y., Sudo, T. and Hoshino, M. |journal = Agric. Biol. Chem. |year = 1989 |volume = 53 |pages = 1663–1669 |pmid = }}</ref><ref>{{cite journal | title = Properties of a new enzyme, nucleoside oxidase, from <em>Pseudomonas maltophilia</em> LB-86 |author = Isono, Y., Sudo, T. and Hoshino, M. |journal = Agric. Biol. Chem. |year = 1989 |volume = 53 |pages = 1671–1677 |pmid = }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[inosine]] + O<sub>2</sub> <math>\rightleftharpoons</math> 9-riburonosylhypoxanthine + H<sub>2</sub>O
: (1a) 2 inosine + O<sub>2</sub> <math>\rightleftharpoons</math> 2 5'-dehydroinosine + 2 H<sub>2</sub>O
: (1b) 2 5'-dehydroinosine + O<sub>2</sub> <math>\rightleftharpoons</math> 2 9-riburonosylhypoxanthine

This enzyme could use other [[purine]] and [[pyrimidine]] [[nucleoside]]s (as well as 2'-[[deoxynucleoside]]s) are substrates.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Nucleoside+oxidase}}

[[Category:EC 1.1.3]]