View source for N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase

{{Infobox enzyme
| Name = (KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase
| EC_number = 2.4.99.13
| CAS_number = 
| IUBMB_EC_number = 2/4/99/13
| GO_code = 
| image = 
| width = 
| caption =
}}
'''(KDO)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase''' ({{EC number|2.4.99.13}}, ''KDO transferase'', ''waaA (gene)'', ''kdtA (gene)'', ''Kdo transferase'', ''3-deoxy-D-manno-oct-2-ulosonic acid transferase'', ''3-deoxy-manno-octulosonic acid transferase'') is an [[enzyme]] with system name ''CMP-3-deoxy-D-manno-oct-2-ulosonate:(KDO)-lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase''.<ref>{{cite journal | title = Biosynthesis of endotoxins. Purification and catalytic properties of 3-deoxy-D-''manno''-octulosonic acid transferase from ''Escherichia coli'' |author = Belunis, C.J. and Raetz, C.R. |journal = J. Biol. Chem. |year = 1992 |volume = 267 |pages = 9988–9997 |pmid = 1577828 | issue = 14}}</ref><ref>{{cite journal | title = Molecular cloning, sequence analysis, and functional characterization of the lipopolysaccharide biosynthetic gene ''kdtA'' encoding  3-deoxy-&alpha;-D-''manno''-octulosonic acid transferase of ''Chlamydia pneumoniae''  strain TW-183 |author = Lobau, S., Mamat, U., Brabetz, W. and Brade, H. |journal = Mol. Microbiol. |year = 1995 |volume = 18 |pages = 391–399 |pmid = 8748024 | doi = 10.1111/j.1365-2958.1995.mmi_18030391.x | issue = 3}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: alpha-Kdo-(2->6)-lipid IVA + CMP-alpha-Kdo <math>\rightleftharpoons</math> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP

The bifunctional enzyme from ''[[Escherichia coli]]'' transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA.

== See also ==
*[[EC 2.4.99.12]], lipid IVA 3-deoxy-D-manno-octulosonic acid transferase

== References ==
{{reflist}}

== External links ==
*{{MeshName|(KDO)-lipid+IVA+3-deoxy-D-manno-octulosonic+acid+transferase}}

[[Category:EC 2.4.99]]