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{{enzyme
| Name = phenylpyruvate decarboxylase
| EC_number = 4.1.1.43
| CAS_number = 37289-45-5
| IUBMB_EC_number = 4/1/1/43
| GO_code = 0050177
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''phenylpyruvate decarboxylase''' ({{EC number|4.1.1.43}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:phenylpyruvate <math>\rightleftharpoons</math> phenylacetaldehyde + CO<sub>2</sub>

Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[phenylpyruvate]], and two [[product (chemistry)|products]], [[phenylacetaldehyde]] and [[carbon dioxide|CO<sub>2</sub>]].

This enzyme belongs to the family of [[lyase]]s, specifically the carboxy-lyases, which cleave carbon-carbon bonds.  The systematic name of this enzyme class is '''phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming)'''. This enzyme is also called '''phenylpyruvate carboxy-lyase'''.  This enzyme participates in [[phenylalanine]] and [[tryptophan]] metabolism.  

==Structural studies==

As of late 2007, only one [[tertiary structure|structure]] has been solved for this class of enzymes, with the [[Protein Data Bank|PDB]] accession code {{PDB link|2NXW}}.

==References==
{{reflist|1}}
* {{cite journal | author = Asakawa T, Wada H, Yamano T | date = 1968 | title = Enzymatic conversion of phenylpyruvate to phenylacetate | journal = Biochim. Biophys. Acta.  | volume = 170 | pages = 375&ndash;91  | pmid = 4303395 | issue = 2 }}

{{4.1-enzyme-stub}}

[[Category:EC 4.1.1]]
[[Category:Enzymes of known structure]]