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{{Infobox enzyme
| Name = Enoyl-CoA hydratase 2
| EC_number = 4.2.1.119
| CAS_number = 
| IUBMB_EC_number = 4/2/1/119
| GO_code = 
| image = 
| width = 
| caption =
}}
'''Enoyl-CoA hydratase 2''' ({{EC number|4.2.1.119}}, ''2-enoyl-CoA hydratase 2'', ''AtECH2'', ''ECH2'', ''MaoC'', ''MFE-2'', ''PhaJAc'', ''D-3-hydroxyacyl-CoA hydro-lyase'', ''D-specific 2-trans-enoyl-CoA hydratase'') is an [[enzyme]] with system name ''(3R)-3-hydroxyacyl-CoA hydro-lyase''.<ref>{{cite journal | title = Crystal structure of 2-enoyl-CoA hydratase 2 from human peroxisomal multifunctional enzyme type 2 |author = Koski, K.M., Haapalainen, A.M., Hiltunen, J.K. and Glumoff, T. |journal = J. Mol. Biol. |date = 2005 |volume = 345 |pages = 1157-1169 |pmid = 15644212}}</ref><ref>{{cite journal | title = Expression and characterization of (<em>R</em>)-specific enoyl coenzyme A hydratase involved in polyhydroxyalkanoate biosynthesis by <em>Aeromonas caviae</em> |author = Fukui, T., Shiomi, N. and Doi, Y. |journal = J. Bacteriol. |date = 1998 |volume = 180 |pages = 667-673 |pmid = 9457873}}</ref><ref>{{cite journal | title = Crystallization and preliminary crystallographic data of 2-enoyl-CoA hydratase 2 domain of <em>Candida tropicalis</em> peroxisomal multifunctional  enzyme type 2 |author = Koski, M.K., Haapalainen, A.M., Hiltunen, J.K. and Glumoff, T. |journal = Acta Crystallogr. D Biol. Crystallogr. |date = 2003 |volume = 59 |pages = 1302-1305 |pmid = 12832794}}</ref><ref>{{cite journal | title = Crystallization and preliminary X-ray analysis of (<em>R</em>)-specific enoyl-CoA hydratase from <em>Aeromonas caviae</em> involved in polyhydroxyalkanoate  biosynthesis |author = Hisano, T., Fukui, T., Iwata, T. and Doi, Y. |journal = Acta Crystallogr. D Biol. Crystallogr. |date = 2001 |volume = 57 |pages = 145-147 |pmid = 11134939}}</ref><ref>{{cite journal | title = Identification and functional characterization of a monofunctional peroxisomal enoyl-CoA hydratase 2 that participates in the degradation of  even <em>cis</em>-unsaturated fatty acids in <em>Arabidopsis thaliana</em> |author = Goepfert, S., Hiltunen, J.K. and Poirier, Y. |journal = J. Biol. Chem. |date = 2006 |volume = 281 |pages = 35894-35903 |pmid = 16982622}}</ref><ref>{{cite journal | title = Evidence for a peroxisomal fatty acid &beta;-oxidation involving <small>D</small>-3-hydroxyacyl-CoAs. Characterization of two forms of hydro-lyase that  convert <small>D</small>-(-)-3-hydroxyacyl-CoA into 2-<em>trans</em>-enoyl-CoA |author = Engeland, K. and Kindl, H. |journal = Eur. J. Biochem. |date = 1991 |volume = 200 |pages = 171-178 |pmid = 1879422}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: (3R)-3-hydroxyacyl-CoA <math>\rightleftharpoons</math> (2E)-2-enoyl-CoA + H<sub>2</sub>O

This enzyme catalyses a hydration step in peroxisomal beta-oxidation.

== References ==
{{reflist}}

== External links ==
* {{MeshName|Enoyl-CoA+hydratase+2}}

[[Category:EC 4.2.1]]