View source for Palmitoyl(protein) hydrolase

{{enzyme
| Name = phosphatidylinositol deacylase
| EC_number = 3.1.1.52
| CAS_number = 81604-94-6
| IUBMB_EC_number = 3/1/1/52
| GO_code = 0050185
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''phosphatidylinositol deacylase''' ({{EC number|3.1.1.52}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:1-phosphatidyl-D-myo-inositol + H<sub>2</sub>O <math>\rightleftharpoons</math> 1-acylglycerophosphoinositol + a carboxylate

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[1-phosphatidyl-D-myo-inositol]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[1-acylglycerophosphoinositol]] and [[carboxylate]].

This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on carboxylic [[ester]] bonds.  The systematic name of this enzyme class is '''1-phosphatidyl-D-myo-inositol 2-acylhydrolase'''. Other names in common use include '''phosphatidylinositol phospholipase A2''', and '''phospholipase A2'''.  

==References==
{{reflist|1}}
* {{cite journal | author = Gray NC, Strickland KP | date = 1982 | title = The purification and characterization of a phospholipase A2 activity from the 106,000 X g pellet (microsomal fraction) of bovine brain acting on phosphatidylinositol | journal = Can. J. Biochem.  | volume = 60 | pages = 108&ndash;17  | pmid = 7083039 | issue = 2 }}
* {{cite journal | author = Gray NC, Strickland KP | date = 1982 | title = On the specificity of a phospholipase A2 purified from the 106,000 X g pellet of bovine brain | journal = Lipids.  | volume = 17 | pages = 91&ndash;6  | pmid = 7087686 | doi = 10.1007/BF02535181 | issue = 2 }}

{{hydrolase-stub}}

[[Category:EC 3.1.1]]
[[Category:Enzymes of unknown structure]]