View source for TRNA1Val (adenine37-N6)-methyltransferase

{{Infobox enzyme
| Name = DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
| EC_number = 2.1.1.234
| CAS_number = 
| IUBMB_EC_number = 2/1/1/234
| GO_code = 
| image = 
| width = 
| caption =
}}
'''DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase''' ({{EC number|2.1.1.234}}, ''DesVI'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose 3-N,N-dimethyltransferase''.<ref>{{cite journal | title = Expression, purification, and characterization of two <em>N</em>,<em>N</em>-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine |author = Chen, H., Yamase, H., Murakami, K., Chang, C.W., Zhao, L., Zhao, Z. and Liu, H.W. |journal = Biochemistry |year = 2002 |volume = 41 |pages = 9165–9183 |pmid = 12119032}}</ref><ref>{{cite journal | title = Three-dimensional structure of DesVI from <em>Streptomyces venezuelae</em>: a sugar <em>N</em>,<em>N</em>-dimethyltransferase required for dTDP-desosamine biosynthesis |author = Burgie, E.S. and Holden, H.M. |journal = Biochemistry |year = 2008 |volume = 47 |pages = 3982–3988 |pmid = 18327916}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: 2 [[S-adenosyl-L-methionine]] + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose <math>\rightleftharpoons</math> 2 [[S-adenosyl-L-homocysteine]] + dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose

The enzyme is involved in the biosynthesis of [[desosamine]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose+N,N-dimethyltransferase}}

[[Category:EC 2.1.1]]