View source for TRNA (guanine37-N1)-methyltransferase

{{Infobox enzyme
| Name = L-olivosyl-oleandolide 3-O-methyltransferase
| EC_number = 2.1.1.239
| CAS_number = 
| IUBMB_EC_number = 2/1/1/239
| GO_code = 
| image = 
| width = 
| caption =
}}
'''L-olivosyl-oleandolide 3-O-methyltransferase''' ({{EC number|2.1.1.239}}, ''OleY'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:L-olivosyl-oleandolide B 3-O-methyltransferase''.<ref>{{cite journal | title = Functional analysis of OleY <small>L</small>-oleandrosyl 3-<em>O</em>-methyltransferase of the oleandomycin biosynthetic pathway in <em>Streptomyces antibioticus</em> |author = Rodriguez, L., Rodriguez, D., Olano, C., Brana, A.F., Mendez, C. and Salas, J.A. |journal = J. Bacteriol. |year = 2001 |volume = 183 |pages = 5358–5363 |pmid = 11514520}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[S-adenosyl-L-methionine]] + L-olivosyl-oleandolide <math>\rightleftharpoons</math> [[S-adenosyl-L-homocysteine]] + L-oleandrosyl-oleandolide 

The enzyme is involved in the [[biosynthesis]] of the [[macrolide]] [[antibiotic]] [[oleandomycin]] in ''[[Streptomyces antibioticus]]''.

== References ==
{{reflist}}

== External links ==
* {{MeshName|L-olivosyl-oleandolide+3-O-methyltransferase}}

[[Category:EC 2.1.1]]