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{{enzyme
| Name = tropomyosin kinase
| EC_number = 2.7.11.28
| CAS_number = 90804-56-1
| IUBMB_EC_number = 2/7/11/28
| GO_code = 0050359
| image = 
| width = 
| caption = 
}}
In [[enzymology]], a '''tropomyosin kinase''' ({{EC number|2.7.11.28}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:ATP + tropomyosin <math>\rightleftharpoons</math> ADP + O-phosphotropomyosin

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]] and [[tropomyosin]], whereas its two [[product (chemistry)|products]] are [[adenosine diphosphate|ADP]] and [[O-phosphotropomyosin]].

This enzyme belongs to the family of [[transferase]]s, specifically those transferring a phosphate group to the sidechain [[oxygen]] atom of [[serine]] or [[threonine]] residues in [[protein]]s ([[protein-serine/threonine kinase]]s).  The systematic name of this enzyme class is '''ATP:tropomyosin O-phosphotransferase'''. Other names in common use include '''tropomyosin kinase (phosphorylating)''', and '''STK'''.  

==References==
{{reflist|1}}
* {{cite journal | author = deBelle I, Mak AS | date = 1987 | title = Isolation and characterization of tropomyosin kinase from chicken embryo | journal = Biochim. Biophys. Acta.  | volume = 925 | pages = 17&ndash;26  | pmid = 3593768 | issue = 1 }}
* {{cite journal | author = Montgomery K, Mak AS | date = 1984 | title = In vitro phosphorylation of tropomyosin by a kinase from chicken embryo | journal = J. Biol. Chem.  | volume = 259 | pages = 5555&ndash;60  | pmid = 6325440 | issue = 9 }}
* {{cite journal | author = Watson MH, Taneja AK, Hodges RS, Mak AS | date = 1988 | title = Phosphorylation of alpha alpha- and beta beta-tropomyosin and synthetic peptide analogues | journal = Biochemistry.  | volume = 27 | pages = 4506&ndash;12  | pmid = 3166994 | doi = 10.1021/bi00412a043 | issue = 12 }}

{{enzyme-stub}}

[[Category:EC 2.7.11]]
[[Category:Enzymes of unknown structure]]