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{{Infobox enzyme
| Name = 23S rRNA (adenine<sup>1618</sup>-N<sup>6</sup>)-methyltransferase
| EC_number = 2.1.1.181
| CAS_number = 
| IUBMB_EC_number = 2/1/1/181
| GO_code = 
| image = 
| width = 
| caption =
}}
'''23S rRNA (adenine<sup>1618</sup>-N<sup>6</sup>)-methyltransferase''' ({{EC number|2.1.1.181}}, ''rRNA large subunit methyltransferase F'', ''YbiN protein'', ''rlmF (gene)'', ''m6A1618 methyltransferase'') is an [[enzyme]] with system name ''S-adenosyl-L-methionine:23S rRNA (adenine<sup>1618</sup>-N<sup>6</sup>)-methyltransferase''.<ref>{{cite journal | title = The ''ybiN'' gene of ''Escherichia coli'' encodes adenine-''N''<sup>6</sup> methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated  residue located close to the ribosomal exit tunnel |author = Sergiev, P.V., Serebryakova, M.V., Bogdanov, A.A. and Dontsova, O.A. |journal = J. Mol. Biol. |year = 2008 |volume = 375 |pages = 291–300 |pmid = 18021804}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]

: [[S-adenosyl-L-methionine]] + adenine<sup>1618</sup> in [[Ribosomal RNA|23S rRNA]] <math>\rightleftharpoons</math> [[S-adenosyl-L-homocysteine]] + N<sup>6</sup>-[[methyladenine]]<sup>1618</sup> in 23S rRNA

The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit.

== References ==
{{reflist}}

== External links ==
* {{MeshName|23S+rRNA+(adenine1618-N6)-methyltransferase}}

[[Category:EC 2.1.1]]