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{{Technical|date=October 2009}}
 
{{enzyme
| Name = glycerophospholipid arachidonoyl-transferase (CoA-independent)
| EC_number = 2.3.1.147
| CAS_number = 102347-79-5
| IUBMB_EC_number = 2/3/1/147
| GO_code = 0047177
| image =
| width =
| caption =
}}
In the field of [[enzymology]], a '''glycerophospholipid arachidonoyl-transferase (CoA-independent)''' ({{EC number|2.3.1.147}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]:
 
:1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine <math>\rightleftharpoons</math> 1-organyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine + 1-organyl-2-lyso-sn-glycero-3-phosphocholine
 
This enzyme catalyzes the transfer of [[arachidonic acid]] and other polyenoic fatty acids from intact [[choline]] or [[ethanolamine]]-containing [[glycerophospholipid]]s to the sn-2 position of a lyso- glycerophospholipid. The organyl group on sn-1 of the donor or acceptor molecule can be alkyl, acyl or alk-1-enyl. This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups.
 
== Nomenclature ==
 
The systematic name of this enzyme class is '''1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lys o-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)'''.
 
==References==
{{Reflist|1}}
* {{Cite journal| author = Robinson M, Blank ML, Snyder F | date = 1985 | title = Acylation of lysophospholipids by rabbit alveolar macrophages Specificities of CoA-dependent and CoA-independent reactions | journal = J. Biol. Chem. | volume = 260 | pages = 7889&ndash;95  | pmid = 4008481 | issue = 13 }}
* {{Cite journal| author = Snyder F, Lee TC, Blank ML | date = 1992 | title = The role of transacylases in the metabolism of arachidonate and platelet activating factor | journal = Prog. Lipid. Res| volume = 31 | pages = 65&ndash;86  | pmid = 1641397 | doi = 10.1016/0163-7827(92)90016-C | issue = 1 }}
 
{{DEFAULTSORT:Glycerophospholipid Arachidonoyl-Transferase (Coa-Independent)}}
[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]
 
 
{{Transferase-stub}}

Latest revision as of 21:41, 17 March 2013

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Template:Enzyme In the field of enzymology, a glycerophospholipid arachidonoyl-transferase (CoA-independent) (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction:

1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine 1-organyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine + 1-organyl-2-lyso-sn-glycero-3-phosphocholine

This enzyme catalyzes the transfer of arachidonic acid and other polyenoic fatty acids from intact choline or ethanolamine-containing glycerophospholipids to the sn-2 position of a lyso- glycerophospholipid. The organyl group on sn-1 of the donor or acceptor molecule can be alkyl, acyl or alk-1-enyl. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups.

Nomenclature

The systematic name of this enzyme class is 1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lys o-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent).

References

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Template:Transferase-stub