3-hydroxyacyl-CoA dehydrogenase: Difference between revisions

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m References: Added 1 doi to a journal cite using AWB (10213)
 
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{{enzyme
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| Name = 3-methylbutanal reductase
| EC_number = 1.1.1.265
| CAS_number =
| IUBMB_EC_number = 1/1/1/265
| GO_code = 0046568
| image =
| width =
| caption =
}}
In [[enzymology]], a '''3-methylbutanal reductase''' ({{EC number|1.1.1.265}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:3-methylbutanol + NAD(P)+ <math>\rightleftharpoons</math> 3-methylbutanal + NAD(P)H + H<sup>+</sup>
 
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[3-methylbutanol]], [[nicotinamide adenine dinucleotide|NAD<sup>+</sup>]], and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 4 [[product (chemistry)|products]] are [[3-methylbutanal]], [[nicotinamide adenine dinucleotide|NADH]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''3-methylbutanol:NAD(P)<sup>+</sup> oxidoreductase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = van Iersel MF, Eppink MH, van Berkel WJ, Rombouts FM, Abee T | date = 1997 | title = Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from ''Saccharomyces cerevisiae'' | journal = Appl. Environ. Microbiol. | volume = 63 | pages = 4079&ndash;82 | pmid = 9327572 | issue = 10 | pmc = 168719 }}
* {{cite journal | author = Bertaglia E, Shah D | date = 2005 | title = Typical atrial flutter ablation and the risk of postablation atrial fibrillation | journal = Ital. Heart. J. | volume = 6 | pages = 946&ndash;9 | pmid = 16502707 | issue = 12 }}
 
{{1.1.1-enzyme-stub}}
 
[[Category:EC 1.1.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:NADH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 11:44, 26 May 2014

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