|
|
| Line 1: |
Line 1: |
| {{enzyme
| | Roger is the identify people today use to contact me but I never ever actually liked that name. For a long time I've been operating as an office environment supervisor. To do [http://www.dict.cc/?s=interior+design interior design] is a little something my wife will not really like but I do. For many years I've been living in Nevada. You can find my website listed here: http://www.voluntarioscanarias.com/cursos/baratas/nike-air-max-2013-blue-baratas.cfm<br><br>my web-site; [http://www.voluntarioscanarias.com/cursos/baratas/nike-air-max-2013-blue-baratas.cfm nike air max 2013 blue] |
| | Name = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase
| |
| | EC_number = 6.2.1.28
| |
| | CAS_number = 118732-03-9
| |
| | IUBMB_EC_number = 6/2/1/28
| |
| | GO_code = 0047476
| |
| | image =
| |
| | width =
| |
| | caption =
| |
| }}
| |
| In [[enzymology]], a '''3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase''' ({{EC number|6.2.1.28}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
| |
| | |
| :ATP + (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate + CoA <math>\rightleftharpoons</math> AMP + diphosphate + (25R)-3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
| |
| | |
| The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[adenosine triphosphate|ATP]], [[(25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate]], and [[coenzyme A|CoA]], whereas its 3 [[product (chemistry)|products]] are [[adenosine monophosphate|AMP]], [[diphosphate]], and [[(25R)-3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA]].
| |
| | |
| This enzyme belongs to the family of [[ligase]]s, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is '''(25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate:CoA ligase (AMP-forming)'''. Other names in common use include '''3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase''', '''DHCA-CoA ligase''', and '''3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)'''. This enzyme participates in [[bile acid biosynthesis]].
| |
| | |
| ==References==
| |
| {{reflist|1}}
| |
| * {{cite journal | author = Prydz K, Kase BF, Bjorkhem I, Pedersen JI | year = 1988 | title = Subcellular localization of 3 alpha, 7 alpha-dihydroxy- and 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoyl-coenzyme A ligase(s) in rat liver | journal = J. Lipid. Res. | volume = 29 | pages = 997–1004 | pmid = 3183523 | issue = 8 }}
| |
| | |
| {{DEFAULTSORT:3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase}}
| |
| [[Category:EC 6.2.1]]
| |
| [[Category:Enzymes of unknown structure]]
| |
| | |
| | |
| {{ligase-stub}}
| |
Roger is the identify people today use to contact me but I never ever actually liked that name. For a long time I've been operating as an office environment supervisor. To do interior design is a little something my wife will not really like but I do. For many years I've been living in Nevada. You can find my website listed here: http://www.voluntarioscanarias.com/cursos/baratas/nike-air-max-2013-blue-baratas.cfm
my web-site; nike air max 2013 blue