Dihydrodipicolinate synthase: Difference between revisions

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{{enzyme
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| Name = ethanolamine-phosphate phospho-lyase
| EC_number = 4.2.3.2
| CAS_number = 37290-88-3
| IUBMB_EC_number = 4/2/3/2
| GO_code = 0050459
| image =
| width =
| caption =
}}
In [[enzymology]], an '''ethanolamine-phosphate phospho-lyase''' ({{EC number|4.2.3.2}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:ethanolamine phosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> acetaldehyde + NH<sub>3</sub> + phosphate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[ethanolamine phosphate]] and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[acetaldehyde]], [[ammonia|NH<sub>3</sub>]], and [[phosphate]].
 
This enzyme belongs to the family of [[lyase]]s, specifically those carbon-oxygen lyases acting on phosphates.  The systematic name of this enzyme class is '''ethanolamine-phosphate phosphate-lyase (deaminating acetaldehyde-forming)'''. Other names in common use include '''O-phosphoethanolamine-phospholyase''', '''amino alcohol O-phosphate phospholyase''', '''O-phosphorylethanol-amine phospho-lyase''', and '''ethanolamine-phosphate phospho-lyase (deaminating)'''.  It employs one [[cofactor (biochemistry)|cofactor]], [[pyridoxal phosphate]]. 
 
==References==
{{reflist|1}}
* {{cite journal | author = Fleshood HL, Pitot HC | date = 1970 | title = The metabolism of O-phosphorylethanolamine in animal tissues. I O-phosphorylethanolamine phospho-lyase: partial purification and characterization | journal = J. Biol. Chem.  | volume = 245 | pages = 4414&ndash;20  | pmid = 5498429 | issue = 17 }}
* {{cite journal | author = Jones A, Faulkner A, Turner JM | date = 1973 | title = Microbial metabolism of amino alcohols. Metabolism of ethanolamine and 1-aminopropan-2-ol in species of Erwinia and the roles of amino alcohol kinase and amino alcohol o-phosphate phospho-lyase in aldehyde formation | journal = Biochem. J. | volume = 134 | pages = 959&ndash;68  | pmid = 4357716 | issue = 4 | pmc = 1177904 }}
 
{{4.2-enzyme-stub}}
 
[[Category:EC 4.2.3]]
[[Category:Pyridoxal phosphate enzymes]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 17:15, 18 July 2014

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