12-hydroxydihydrochelirubine 12-O-methyltransferase: Difference between revisions

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{{enzyme
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| Name = 3-methylquercitin 7-O-methyltransferase
| EC_number = 2.1.1.82
| CAS_number = 96477-62-2
| IUBMB_EC_number = 2/1/1/82
| GO_code = 0030757
| image =
| width =
| caption =
}}
In [[enzymology]], a '''3-methylquercetin 7-O-methyltransferase''' ({{EC number|2.1.1.82}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:S-adenosyl-L-methionine + 5,7,3',4'-tetrahydroxy-3-methoxyflavone <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + 5,3',4'-trihydroxy-3,7-dimethoxyflavone
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[5,7,3',4'-tetrahydroxy-3-methoxyflavone]] (isorhamnetin), whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[5,3',4'-trihydroxy-3,7-dimethoxyflavone]] (rhamnazin).
 
This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases.  The systematic name of this enzyme class is '''S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase'''. Other names in common use include '''flavonol 7-O-methyltransferase''', '''flavonol 7-methyltransferase''', '''7-OMT''', '''S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone''', '''7-O-methyltransferase''', and '''3-methylquercitin 7-O-methyltransferase [mis-spelt]'''.
 
The enzyme can be found in ''[[Chrysosplenium americanum]]''  (American Golden Saxifrage).
 
==References==
{{reflist|1}}
* {{cite journal | author = De Luca V, Ibrahim RK | date = 1985 | title = Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases | journal = Arch. Biochem. Biophys.  | volume = 238 | pages = 596&ndash;605  | pmid = 3994393 | doi = 10.1016/0003-9861(85)90205-X | issue = 2 }}
 
{{transferase-stub}}
 
[[Category:EC 2.1.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 18:11, 20 June 2014

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