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| {{enzyme
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| | Name = 7-methylxanthosine synthase
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| | EC_number = 2.1.1.158
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| | CAS_number =
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| | IUBMB_EC_number = 2/1/1/158
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| | GO_code =
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| In [[enzymology]], a '''7-methylxanthosine synthase''' ({{EC number|2.1.1.158}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :S-adenosyl-L-methionine + xanthosine <math>\rightleftharpoons</math> S-adenosyl-L-homocysteine + 7-methylxanthosine
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[S-Adenosyl methionine|S-adenosyl methionine]] and [[xanthosine]], whereas its two [[product (chemistry)|products]] are [[S-adenosylhomocysteine]] and [[7-methylxanthosine]].
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| This enzyme belongs to the family of [[transferase]]s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is '''S-adenosyl-L-methionine:xanthosine N7-methyltransferase'''. Other names in common use include '''xanthosine methyltransferase''', '''XMT''', '''xanthosine:S-adenosyl-L-methionine methyltransferase''', '''CtCS1''', '''CmXRS1''', '''CaXMT1''', and '''S-adenosyl-L-methionine:xanthosine 7-N-methyltransferase'''.
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Negishi O, Ozawa T and Imagawa H | date = 1985 | title = The role of xanthosine in the biosynthesis of caffeine in coffee plants | journal = Agric. Biol. Chem. | volume = 49 | pages = 2221–2222 }}
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| * {{cite journal | author = Mizuno K, Kato M, Irino F, Yoneyama N, Fujimura T, Ashihara H | date = 2003 | title = The first committed step reaction of caffeine biosynthesis: 7-methylxanthosine synthase is closely homologous to caffeine synthases in coffee (Coffea arabica L.) | journal = FEBS. Lett. | volume = 547 | pages = 56–60 | pmid = 12860386 | doi = 10.1016/S0014-5793(03)00670-7 | issue = 1-3 }}
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| * {{cite journal | author = Uefuji H, Ogita S, Yamaguchi Y, Koizumi N, Sano H | date = 2003 | title = Molecular cloning and functional characterization of three distinct N-methyltransferases involved in the caffeine biosynthetic pathway in coffee plants | journal = Plant. Physiol. | volume = 132 | pages = 372–80 | pmid = 12746542 | doi = 10.1104/pp.102.019679 | issue = 1 | pmc = 166982 }}
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| * {{cite journal | author = Yoneyama N, Morimoto H, Ye CX, Ashihara H, Mizuno K, Kato M | date = 2006 | title = Substrate specificity of N-methyltransferase involved in purine alkaloids synthesis is dependent upon one amino acid residue of the enzyme | journal = Mol. Genet. Genomics. | volume = 275 | pages = 125–35 | pmid = 16333668 | doi = 10.1007/s00438-005-0070-z | issue = 2 }}
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| {{transferase-stub}}
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| [[Category:EC 2.1.1]]
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| [[Category:Enzymes of unknown structure]]
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Alyson Meagher is the name her parents gave her but she doesn't like when people use her full title. To play lacross is something I really appreciate performing. Office supervising is what she does for a living. I've always loved living in Alaska.
Also visit my weblog: free psychic readings