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| Name = gentamicin 2'-N-acetyltransferase
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| EC_number = 2.3.1.59
| CAS_number = 50864-40-9
| IUBMB_EC_number = 2/3/1/59
| GO_code = 0047921
| image =  
| width =  
| caption =
}}
In [[enzymology]], a '''gentamicin 2'-N-acetyltransferase''' ({{EC number|2.3.1.59}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:acetyl-CoA + gentamicin C<sub>1</sub>a <math>\rightleftharpoons</math> CoA + N<sub>2</sub>'-acetylgentamicin C<sub>1</sub>a
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[acetyl-CoA]] and [[gentamicin|gentamicin C1a]], whereas its two [[product (chemistry)|products]] are [[coenzyme A|CoA]] and N2'-acetyl gentamicin C1a.
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is '''acetyl-CoA:gentamicin-C1a N2'-acetyltransferase'''. Other names in common use include '''gentamicin acetyltransferase II''', '''gentamicin 2'-N-acetyltransferase''', and '''acetyl-CoA:gentamicin-C1a N2'-acetyltransferase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Benveniste R, Davies J | date = 1973 | title = Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria | journal = Proc. Natl. Acad. Sci. U.S.A.  | volume = 70 | pages = 2276&ndash;80  | pmid = 4209515 | doi = 10.1073/pnas.70.8.2276 | issue = 8 | pmc = 433717 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 13:03, 27 October 2014

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