3-methyl-2-oxobutanoate dehydrogenase

Template:Enzyme In enzymology, a 4-trimethylammoniobutyraldehyde dehydrogenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

4-trimethylammoniobutanal + NAD⁺ + H₂O $\rightleftharpoons$ 4-trimethylammoniobutanoate + NADH + 2 H⁺

The 3 substrates of this enzyme are 4-trimethylammoniobutanal, NAD⁺, and H₂O, whereas its 3 products are 4-trimethylammoniobutanoate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-trimethylammoniobutanal:NAD+ 1-oxidoreductase. Other names in common use include 4-trimethylaminobutyraldehyde dehydrogenase, and 4-N-trimethylaminobutyraldehyde dehydrogenase. This enzyme participates in lysine degradation and carnitine biosynthesis.

See also

• Carnitine biosynthesis
• γ-Butyrobetaine hydroxylase
• N^ε-Trimethyllysine hydroxylase

References

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