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| {{DISPLAYTITLE:15-hydroxyprostaglandin-I dehydrogenase (NADP<sup>+</sup>)}}
| | Jayson Berryhill is how I'm called and my spouse doesn't like it at all. Since I was 18 I've been operating as a bookkeeper but quickly my wife and I will start our own company. Kentucky is where I've always been living. The preferred hobby for him and his children is to play lacross and he'll be starting something else along with it.<br><br>Look at my weblog - [http://www.seekavideo.com/playlist/2199/video/ real psychics] |
| {{enzyme
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| | Name = 15-hydroxyprostaglandin-I dehydrogenase (NADP<sup>+</sup>)
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| | EC_number = 1.1.1.231
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| | CAS_number = 79468-49-8
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| | IUBMB_EC_number = 1/1/1/231
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| | GO_code = 0047033
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| In [[enzymology]], a '''15-hydroxyprostaglandin-I dehydrogenase (NADP<sup>+</sup>)''' ({{EC number|1.1.1.231}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13- dienoate + NADP<sup>+</sup> <math>\rightleftharpoons</math> (5Z,13E)-6,9alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH + H<sup>+</sup>
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| The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-]], [[dienoate]], and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[(5Z,13E)-6,9alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
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| This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is '''(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoa te:NADP<sup>+</sup> 15-oxidoreductase'''. Other names in common use include '''prostacyclin dehydrogenase''', '''PG I2 dehydrogenase''', '''prostacyclin dehydrogenase''', '''NADP<sup>+</sup>-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase''', '''NADP<sup>+</sup>-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase''', and '''15-hydroxyprostaglandin-I dehydrogenase (NADP<sup>+</sup>)'''.
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = Korff JM, Jarabak J | date = 1982 | title = Isolation and properties of an NADP<sup>+</sup>-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase from rabbit kidney | journal = Methods Enzymol. | volume = 86 | pages = 152–5 | pmid = 6182444 | doi = 10.1016/0076-6879(82)86185-5 }}
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| {{1.1.1-enzyme-stub}}
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| [[Category:EC 1.1.1]]
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| [[Category:NADPH-dependent enzymes]]
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| [[Category:Enzymes of unknown structure]]
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Jayson Berryhill is how I'm called and my spouse doesn't like it at all. Since I was 18 I've been operating as a bookkeeper but quickly my wife and I will start our own company. Kentucky is where I've always been living. The preferred hobby for him and his children is to play lacross and he'll be starting something else along with it.
Look at my weblog - real psychics