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{{enzyme
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| Name = 1-alkylglycerophosphocholine O-acetyltransferase
| EC_number = 2.3.1.67
| CAS_number = 76773-96-1
| IUBMB_EC_number = 2/3/1/67
| GO_code = 0047192
| image =
| width =
| caption =
}}
In [[enzymology]], a '''1-alkylglycerophosphocholine O-acetyltransferase''' ({{EC number|2.3.1.67}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine <math>\rightleftharpoons</math> CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[acetyl-CoA]] and [[1-alkyl-sn-glycero-3-phosphocholine]], whereas its two [[product (chemistry)|products]] are [[coenzyme A|CoA]] and [[2-acetyl-1-alkyl-sn-glycero-3-phosphocholine]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups.  The systematic name of this enzyme class is '''acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase'''. Other names in common use include '''acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine''', '''2-O-acetyltransferase''', '''acetyl-CoA:lyso-PAF acetyltransferase''', '''1-alkyl-2-lysolecithin acetyltransferase''', '''acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase''', '''blood platelet-activating factor acetyltransferase''', '''lyso-GPC:acetyl CoA acetyltransferase''', '''lyso-platelet activating factor:acetyl-CoA acetyltransferase''', '''lysoPAF:acetyl CoA acetyltransferase''', '''PAF acetyltransferase''', '''platelet-activating factor acylhydrolase''', '''platelet-activating factor-synthesizing enzyme''', '''1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase''', and '''lyso-platelet-activating factor:acetyl-CoA acetyltransferase'''. This enzyme participates in [[ether lipid metabolism]]. 
 
==References==
{{reflist|1}}
* {{cite journal | author = Wykle RL, Malone B, Snyder F | date = 1980 | title = Enzymatic synthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, a hypotensive and platelet-aggregating lipid | journal = J. Biol. Chem.  | volume = 255 | pages = 10256&ndash;60  | pmid = 7430122 | issue = 21 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 01:51, 1 January 2015

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