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| {{enzyme
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| | Name = amylosucrase
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| | EC_number = 2.4.1.4
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| | CAS_number = 9032-11-5
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| | IUBMB_EC_number = 2/4/1/4
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| | GO_code = 0047669
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| In [[enzymology]], an '''amylosucrase''' ({{EC number|2.4.1.4}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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| :sucrose + (1,4-alpha-D-glucosyl)n <math>\rightleftharpoons</math> D-fructose + (1,4-alpha-D-glucosyl)n<sup>+</sup>1
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| Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[sucrose]] and [[(1,4-alpha-D-glucosyl)n]], whereas its two [[product (chemistry)|products]] are [[D-fructose]] and [[(1,4-alpha-D-glucosyl)n+1]].
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| This enzyme belongs to the family of [[glycosyltransferase]]s, specifically the hexosyltransferases. The systematic name of this enzyme class is '''sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase'''. Other names in common use include '''sucrose-glucan glucosyltransferase''', and '''sucrose-1,4-alpha-glucan glucosyltransferase'''. This enzyme participates in [[starch and sucrose metabolism]].
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| ==Structural studies==
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| As of late 2007, 10 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1G5A}}, {{PDB link|1JG9}}, {{PDB link|1JGI}}, {{PDB link|1MVY}}, {{PDB link|1MW0}}, {{PDB link|1MW1}}, {{PDB link|1MW2}}, {{PDB link|1MW3}}, {{PDB link|1S46}}, and {{PDB link|1ZS2}}.
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| ==References==
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| {{reflist|1}}
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| * {{cite journal | author = AVIGAD G, FEINGOLD DS, HESTRIN S | date = 1957 | title = Enzymatic synthesis and reactions of a sucrose isomer alpha-D-galactopyranosyl-beta-D-fructofuranoside | journal = J. Biol. Chem. | volume = 224 | pages = 295–307 | pmid = 13398406 | issue = 1 }}
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| * {{cite journal | author = Hehre EJ | date = 1951 | title = Enzymic synthesis of polysaccharides: a biological type of polymerization | journal = Adv. Enzymol. Relat. Subj. Biochem. | volume = 11 | pages = 297–337 | doi = 10.1002/9780470122563.ch6 | series = Advances in Enzymology - and Related Areas of Molecular Biology | isbn = 978-0-470-12256-3 }}
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| * {{cite journal | author = Hehre EJ, Hamilton DM and Carlson AS | date = 1949 | title = Synthesis of a polsaccharide of the starch glycogen class from sucrose by a cell-free, bacterial enzyme system (amylosucrase) | journal = J. Biol. Chem. | volume = 177 | pages = 267–279 }}
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| {{enzyme-stub}}
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| [[Category:EC 2.4.1]]
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| [[Category:Enzymes of known structure]]
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