Operational amplifier applications: Difference between revisions
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The name of | The '''worm-like chain''' (WLC) model in [[polymer physics]] is used to describe the behavior of semi-flexible [[polymers]]; it is the continuous version of the [[Otto Kratky|Kratky]]-[[Günther Porod|Porod]] model. | ||
== Theoretical Considerations == | |||
The WLC model envisions an [[isotropic]] rod that is continuously flexible.<ref name=Doi>{{cite book | author=Doi and Edwards | title=The Theory of Polymer Dynamics | year=1999}}</ref><ref name=Rubinstein>{{cite book | author=Rubinstein and Colby | title=Polymer Physics | year=2003}}</ref><ref name=Kirby>{{cite book | author=Kirby, B.J. | title=Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices | url=http://www.kirbyresearch.com/textbook}}</ref> This is in contrast to the [[Ideal chain|freely-jointed chain]] model that is flexible only between discrete segments. The worm-like chain model is particularly suited for describing stiffer polymers, with successive segments displaying a sort of cooperativity: all pointing in roughly the same direction. At room temperature, the polymer adopts a conformational ensemble that is smoothly curved; at <math>T = 0</math> K, the polymer adopts a rigid rod conformation.<ref name=Doi/> | |||
For a polymer of length <math>l</math>, parametrize the path of the polymer as <math>s \in(0,l)</math>, allow <math>\hat t(s)</math> to be the unit tangent vector to the chain at <math>s</math>, and <math>\vec r(s)</math> to be the position vector along the chain. Then | |||
:<math>\hat t(s) \equiv \frac {\partial \vec r(s) }{\partial s}</math> and the end-to-end distance <math>\vec R = \int_{0}^{l}\hat t(s) ds</math> .<ref name=Doi/> | |||
It can be shown that the orientation [[correlation function]] for a worm-like chain follows an [[exponential decay]]:<ref name=Doi/><ref name=Kirby/> | |||
:<math>\langle\hat t(s) \cdot \hat t(0)\rangle=\langle \cos \; \theta (s)\rangle = e^{-s/P}\,</math>, | |||
where <math>P</math> is by definition the polymer's characteristic [[persistence length]]. A useful value is the mean square end-to-end distance of the polymer:<ref name=Doi/><ref name=Kirby/> | |||
<math> | |||
\begin{align} | |||
\langle R^{2} \rangle & = \langle \vec R \cdot \vec R \rangle \\ | |||
& = \left\langle \int_{0}^{l} \hat t(s) ds \cdot \int_{0}^{l} \hat t(s') ds' \right\rangle \\ | |||
& = \int_{0}^{l} ds \int_{0}^{l} \langle \hat t(s) \cdot \hat t(s') \rangle ds' \\ | |||
& = \int_{0}^{l} ds \int_{0}^{l} e^{-\left | s - s' \right | / P} ds' \\ | |||
\langle R^{2} \rangle & = 2 Pl \left [ 1 - \frac {P}{l} \left ( 1 - e^{-l/P} \right ) \right ] | |||
\end{align} | |||
</math> | |||
* Note that in the limit of <math>l \gg P</math>, then <math>\langle R^{2} \rangle = 2Pl</math>. This can be used to show that a [[Kuhn length|Kuhn segment]] is equal to twice the persistence length of a worm-like chain.<ref name=Rubinstein/> | |||
== Biological Relevance == | |||
Several biologically important polymers can be effectively modeled as worm-like chains, including: | |||
* double-stranded [[DNA]] and [[RNA]];<ref name=Kirby/><ref name=dekker2005>{{cite journal | author=J. A. Abels and F. Moreno-Herrero and T. van der Heijden and C. Dekker and N. H. Dekker | title=Single-Molecule Measurements of the Persistence Length of Double-Stranded RNA | journal=Biophysical Journal| year=2005| volume=88| pages=2737–2744| doi=10.1529/biophysj.104.052811 }}</ref> | |||
* unstructured [[RNA]]; | |||
* unstructured polypeptides ([[proteins]]).<ref name=lapidus2002>{{cite journal | author=L. J. Lapidus and P. J. Steinbach and W. A. Eaton and A. Szabo and J. Hofrichter | title=Single-Molecule Effects of Chain Stiffness on the Dynamics of Loop Formation in Polypeptides. Appendix: Testing a 1-Dimensional Diffusion Model for Peptide Dynamics | journal=Journal of Physical Chemistry B| year=2002| volume=106| pages=11628–11640| doi=10.1021/jp020829v}}</ref> | |||
== Stretching Worm-like Chain Polymers == | |||
At finite temperatures, the distance between the two ends of the polymer (end-to-end distance) will be siginficantly shorter than the contour length <math>L_0</math>. This is caused by thermal fluctuations, which result in a coiled, random configuration of the polymer, when undisturbed. Upon stretching the polymer, the accesible spectrum of fluctuations reduces, which causes an entropic force against the external elongation. | |||
This entropic force can be estimated by considering the entropic Hamiltonian: | |||
<math> H = H_{\rm entropic} + H_{\rm external}= \frac {1}{2}k_B T \int_{0}^{L_0} P \cdot \left (\frac {\partial^2 \vec r(s) }{\partial s^2}\right )^{2} ds - xF</math>. | |||
Here, the [[contour length]] is represented by <math>L_0</math>, the persistence length by <math>P</math>, the extension and external force is represented by extension <math>xF</math>. | |||
Laboratory tools such as [[atomic force microscopy]] (AFM) and [[optical tweezers]] have been used to characterize the force-dependent stretching behavior of the polymers listed above. An interpolation formula that approximates the force-extension behavior is (J. F. Marko, E. D. Siggia (1995)): | |||
:<math>\frac {FP} {k_{B}T} = \frac {1}{4} \left ( 1 - \frac {x} {L_0} \right )^{-2} - \frac {1}{4} + \frac {x}{L_0}</math> | |||
where <math>k_B</math> is the [[Boltzmann constant]] and <math>T</math> is the absolute temperature. | |||
== Extensible Worm-like Chain model == | |||
When extending most polymers, their elastic response cannot be neglected. As an example, for the well-studied case of stretching DNA in physiological conditions (near neutral pH, ionic strength approximately 100 mM) at room temperature, the compliance of the DNA along the contour must be accounted for. This enthalpic compliance is accounted for the material paramter <math>K_0</math>, the stretch modulus. For significantly extended polymers, this yields the following Hamiltonian: | |||
<math> H = H_{\rm entropic}+H_{\rm enthalpic}+H_{\rm external} = \frac {1}{2}k_B T \int_{0}^{L_0} P \cdot \left (\frac {\partial \vec r(s) }{\partial s}\right )^{2} ds + \frac {1}{2}\frac {K_0}{L_0} x^{2} - xF </math>, | |||
with <math>L_0</math>, the contour length, <math>P</math>, the persistence length, <math>x</math> the extension and <math>F</math> external force. This expression takes into account both: The entropic term, which regards changes in the polymer conformation and the enthalpic term, which describes the elongation of the polymer due to the external force. In the expression above, the enthalpic response is described as a linear Hookian spring. | |||
Several approximations have been put forward, dependend on the applied external force. For the low force regime (F < about 10 pN), the following interpolation formula was derived:<ref>{{cite journal|last=Marko|first=J.F.|coauthors=Eric D. Siggia|title=Stretching DNA|journal=Macromolecules|year=1995|volume=28|pages=8759–8770|bibcode = 1995MaMol..28.8759M |doi = 10.1021/ma00130a008 }}</ref> | |||
<math>\frac {FP} {k_{B}T} = \frac {1}{4} \left ( 1 - \frac {x} {L_0} + \frac {F}{K_0} \right )^{-2} - \frac {1}{4} + \frac {x}{L_0} - \frac {F}{K_0}</math>. | |||
For the higher force regime, where the polymer is significantly extended, the following approximation is valid:<ref>{{cite journal|last=Odijk|first=Theo|title=Stiff Chains and Filaments under Tension|journal=Macromolecules|year=1995|volume=28|pages=7016–7018|bibcode = 1995MaMol..28.7016O |doi = 10.1021/ma00124a044 }}</ref> | |||
<math>x = L_0 \left ( 1 - \frac {1} {2} \left ( \frac {k_{B}T}{FP} \right )^{1/2} + \frac {F}{K_0}\right ) </math>. | |||
A typical value for the stretch modulus of double-stranded DNA is around 1000 pN and 45 nm for the persistence length.<ref>{{cite journal|last=Wang|first=Michelle D.|coauthors=Hong Yin, Robert Landick, Jeff Gelles and Steven M. Block|title=Stretching DNA with Optical Tweezers|journal=Biophysical Journal|year=1997|volume=72|pages=1335–1346|bibcode = 1997BpJ....72.1335W |doi = 10.1016/S0006-3495(97)78780-0 }}</ref> | |||
== See also == | |||
* [[Ideal chain]] | |||
* [[Polymer]] | |||
* [[Polymer physics]] | |||
== References == | |||
{{Reflist}} | |||
* [[Otto Kratky|O. Kratky]], [[Günther Porod|G. Porod]] (1949), "Röntgenuntersuchung gelöster Fadenmoleküle." ''Rec. Trav. Chim. Pays-Bas.'' '''68''': 1106-1123. | |||
* J. F. Marko, E. D. Siggia (1995), "Stretching DNA." ''Macromolecules'', '''28''': p. 8759. | |||
* C. Bustamante, J. F. Marko, E. D. Siggia, and S. Smith (1994), "Entropic elasticity of lambda-phage DNA." ''Science'', '''265''': 1599-1600. PMID 8079175 | |||
* M. D. Wang, H. Yin, R. Landick, J. Gelles, and S. M. Block (1997), "Stretching DNA with optical tweezers." ''Biophys. J.'', '''72''':1335-1346. PMID 9138579 | |||
* C. Bouchiat et al., [http://www.biophysj.org/cgi/content/abstract/76/1/409 "Estimating the Persistence Length of a Worm-Like Chain Molecule from Force-Extension Measurements"], Biophys J, January 1999, p. 409-413, Vol. 76, No. 1 | |||
<!-- this is probably more about physics than chemistry, since no reactivity is involved --> | |||
[[Category:Polymer physics]] | |||
[[Category:Polymers]] | |||
<!-- I see no reason this should be excluded from Biophysics category --> | |||
[[Category:Biophysics]] | |||
<!-- [[Category:Biology]] too general --> | |||
<!-- [[Category:Physics]] too general --> |
Revision as of 00:23, 15 January 2014
The worm-like chain (WLC) model in polymer physics is used to describe the behavior of semi-flexible polymers; it is the continuous version of the Kratky-Porod model.
Theoretical Considerations
The WLC model envisions an isotropic rod that is continuously flexible.[1][2][3] This is in contrast to the freely-jointed chain model that is flexible only between discrete segments. The worm-like chain model is particularly suited for describing stiffer polymers, with successive segments displaying a sort of cooperativity: all pointing in roughly the same direction. At room temperature, the polymer adopts a conformational ensemble that is smoothly curved; at K, the polymer adopts a rigid rod conformation.[1]
For a polymer of length , parametrize the path of the polymer as , allow to be the unit tangent vector to the chain at , and to be the position vector along the chain. Then
- and the end-to-end distance .[1]
It can be shown that the orientation correlation function for a worm-like chain follows an exponential decay:[1][3]
where is by definition the polymer's characteristic persistence length. A useful value is the mean square end-to-end distance of the polymer:[1][3]
- Note that in the limit of , then . This can be used to show that a Kuhn segment is equal to twice the persistence length of a worm-like chain.[2]
Biological Relevance
Several biologically important polymers can be effectively modeled as worm-like chains, including:
Stretching Worm-like Chain Polymers
At finite temperatures, the distance between the two ends of the polymer (end-to-end distance) will be siginficantly shorter than the contour length . This is caused by thermal fluctuations, which result in a coiled, random configuration of the polymer, when undisturbed. Upon stretching the polymer, the accesible spectrum of fluctuations reduces, which causes an entropic force against the external elongation. This entropic force can be estimated by considering the entropic Hamiltonian:
Here, the contour length is represented by , the persistence length by , the extension and external force is represented by extension .
Laboratory tools such as atomic force microscopy (AFM) and optical tweezers have been used to characterize the force-dependent stretching behavior of the polymers listed above. An interpolation formula that approximates the force-extension behavior is (J. F. Marko, E. D. Siggia (1995)):
where is the Boltzmann constant and is the absolute temperature.
Extensible Worm-like Chain model
When extending most polymers, their elastic response cannot be neglected. As an example, for the well-studied case of stretching DNA in physiological conditions (near neutral pH, ionic strength approximately 100 mM) at room temperature, the compliance of the DNA along the contour must be accounted for. This enthalpic compliance is accounted for the material paramter , the stretch modulus. For significantly extended polymers, this yields the following Hamiltonian:
with , the contour length, , the persistence length, the extension and external force. This expression takes into account both: The entropic term, which regards changes in the polymer conformation and the enthalpic term, which describes the elongation of the polymer due to the external force. In the expression above, the enthalpic response is described as a linear Hookian spring. Several approximations have been put forward, dependend on the applied external force. For the low force regime (F < about 10 pN), the following interpolation formula was derived:[6]
For the higher force regime, where the polymer is significantly extended, the following approximation is valid:[7]
A typical value for the stretch modulus of double-stranded DNA is around 1000 pN and 45 nm for the persistence length.[8]
See also
References
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- O. Kratky, G. Porod (1949), "Röntgenuntersuchung gelöster Fadenmoleküle." Rec. Trav. Chim. Pays-Bas. 68: 1106-1123.
- J. F. Marko, E. D. Siggia (1995), "Stretching DNA." Macromolecules, 28: p. 8759.
- C. Bustamante, J. F. Marko, E. D. Siggia, and S. Smith (1994), "Entropic elasticity of lambda-phage DNA." Science, 265: 1599-1600. PMID 8079175
- M. D. Wang, H. Yin, R. Landick, J. Gelles, and S. M. Block (1997), "Stretching DNA with optical tweezers." Biophys. J., 72:1335-1346. PMID 9138579
- C. Bouchiat et al., "Estimating the Persistence Length of a Worm-Like Chain Molecule from Force-Extension Measurements", Biophys J, January 1999, p. 409-413, Vol. 76, No. 1
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The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more
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In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang
Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules
Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.
A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running
The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more
There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang - ↑ One of the biggest reasons investing in a Singapore new launch is an effective things is as a result of it is doable to be lent massive quantities of money at very low interest rates that you should utilize to purchase it. Then, if property values continue to go up, then you'll get a really high return on funding (ROI). Simply make sure you purchase one of the higher properties, reminiscent of the ones at Fernvale the Riverbank or any Singapore landed property Get Earnings by means of Renting
In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang
Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules
Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.
A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running
The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more
There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang - ↑ One of the biggest reasons investing in a Singapore new launch is an effective things is as a result of it is doable to be lent massive quantities of money at very low interest rates that you should utilize to purchase it. Then, if property values continue to go up, then you'll get a really high return on funding (ROI). Simply make sure you purchase one of the higher properties, reminiscent of the ones at Fernvale the Riverbank or any Singapore landed property Get Earnings by means of Renting
In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang
Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules
Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.
A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running
The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more
There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang - ↑ One of the biggest reasons investing in a Singapore new launch is an effective things is as a result of it is doable to be lent massive quantities of money at very low interest rates that you should utilize to purchase it. Then, if property values continue to go up, then you'll get a really high return on funding (ROI). Simply make sure you purchase one of the higher properties, reminiscent of the ones at Fernvale the Riverbank or any Singapore landed property Get Earnings by means of Renting
In its statement, the singapore property listing - website link, government claimed that the majority citizens buying their first residence won't be hurt by the new measures. Some concessions can even be prolonged to chose teams of consumers, similar to married couples with a minimum of one Singaporean partner who are purchasing their second property so long as they intend to promote their first residential property. Lower the LTV limit on housing loans granted by monetary establishments regulated by MAS from 70% to 60% for property purchasers who are individuals with a number of outstanding housing loans on the time of the brand new housing purchase. Singapore Property Measures - 30 August 2010 The most popular seek for the number of bedrooms in Singapore is 4, followed by 2 and three. Lush Acres EC @ Sengkang
Discover out more about real estate funding in the area, together with info on international funding incentives and property possession. Many Singaporeans have been investing in property across the causeway in recent years, attracted by comparatively low prices. However, those who need to exit their investments quickly are likely to face significant challenges when trying to sell their property – and could finally be stuck with a property they can't sell. Career improvement programmes, in-house valuation, auctions and administrative help, venture advertising and marketing, skilled talks and traisning are continuously planned for the sales associates to help them obtain better outcomes for his or her shoppers while at Knight Frank Singapore. No change Present Rules
Extending the tax exemption would help. The exemption, which may be as a lot as $2 million per family, covers individuals who negotiate a principal reduction on their existing mortgage, sell their house short (i.e., for lower than the excellent loans), or take part in a foreclosure course of. An extension of theexemption would seem like a common-sense means to assist stabilize the housing market, but the political turmoil around the fiscal-cliff negotiations means widespread sense could not win out. Home Minority Chief Nancy Pelosi (D-Calif.) believes that the mortgage relief provision will be on the table during the grand-cut price talks, in response to communications director Nadeam Elshami. Buying or promoting of blue mild bulbs is unlawful.
A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running
The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more
There are various methods to go about discovering the precise property. Some local newspapers (together with the Straits Instances ) have categorised property sections and many local property brokers have websites. Now there are some specifics to consider when buying a 'new launch' rental. Intended use of the unit Every sale begins with 10 p.c low cost for finish of season sale; changes to 20 % discount storewide; follows by additional reduction of fiftyand ends with last discount of 70 % or extra. Typically there is even a warehouse sale or transferring out sale with huge mark-down of costs for stock clearance. Deborah Regulation from Expat Realtor shares her property market update, plus prime rental residences and houses at the moment available to lease Esparina EC @ Sengkang