6,7-dihydropteridine reductase

Template:Enzyme Aralkylamine dehydrogenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

RCH₂NH₂ + H₂O + acceptor $\rightleftharpoons$ RCHO + NH₃ + reduced acceptor

The 3 substrates of this enzyme are RCH₂NH₂, water, and an acceptor, whereas its 3 products are RCHO, ammonia, and a reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with other acceptors. The systematic name of this enzyme class is aralkylamine:acceptor oxidoreductase (deaminating). Other names in common use include aromatic amine dehydrogenase, dehydrogenase, arylamine, tyramine dehydrogenase, aromatic amine dehydrogenase, and aralkylamine:(acceptor) oxidoreductase (deaminating). This enzyme participates in tyrosine metabolism and phenylalanine metabolism.

Structural studies

As of late 2007, 23 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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