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| Name = phorbol-diester hydrolase
| EC_number = 3.1.1.51
| CAS_number = 81181-74-0
| IUBMB_EC_number = 3/1/1/51
| GO_code = 0050181
| image =  
| width =  
| caption =  
}}
In [[enzymology]], a '''phorbol-diester hydrolase''' ({{EC number|3.1.1.51}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:phorbol 12,13-dibutanoate + H<sub>2</sub>O <math>\rightleftharpoons</math> phorbol 13-butanoate + butanoate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[phorbol 12,13-dibutanoate]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[phorbol 13-butanoate]] and [[butanoate]].
 
This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on carboxylic [[ester]] bonds. The systematic name of this enzyme class is '''12,13-diacylphorbate 12-acylhydrolase'''. Other names in common use include '''diacylphorbate 12-hydrolase''', '''diacylphorbate 12-hydrolase''', '''phorbol-12,13-diester 12-ester hydrolase''', and '''PDEH'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Shoyab M, Warren TC, Todaro GJ | date = 1981 | title = Isolation and characterization of an ester hydrolase active on phorbol diesters from murine liver | journal = J. Biol. Chem. | volume = 256 | pages = 12529&ndash;34  | pmid = 6946062 | issue = 23 }}
 
{{hydrolase-stub}}
 
[[Category:EC 3.1.1]]
[[Category:Enzymes of unknown structure]]

Revision as of 22:21, 17 March 2013

Template:Enzyme In enzymology, a phorbol-diester hydrolase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

phorbol 12,13-dibutanoate + H2O phorbol 13-butanoate + butanoate

Thus, the two substrates of this enzyme are phorbol 12,13-dibutanoate and H2O, whereas its two products are phorbol 13-butanoate and butanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 12,13-diacylphorbate 12-acylhydrolase. Other names in common use include diacylphorbate 12-hydrolase, diacylphorbate 12-hydrolase, phorbol-12,13-diester 12-ester hydrolase, and PDEH.

References

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