1-alkylglycerophosphocholine O-acetyltransferase

Template:Enzyme In enzymology, a 2-hydroxyglutarate synthase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

propanoyl-CoA + H₂O + glyoxylate $\rightleftharpoons$ 2-hydroxyglutarate + CoA

The 3 substrates of this enzyme are propanoyl-CoA, H₂O, and glyoxylate, whereas its two products are 2-hydroxyglutarate and CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming). Other names in common use include 2-hydroxyglutaratic synthetase, 2-hydroxyglutaric synthetase, alpha-hydroxyglutarate synthase, hydroxyglutarate synthase, and 2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating). This enzyme participates in c5-branched dibasic acid metabolism.

See also

• D2HGDH
• L2HGDH
• 2-hydroxyglutarate dehydrogenase
• 2-Hydroxyglutaric aciduria
• Hydroxyacid-oxoacid transhydrogenase

References

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