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{{enzyme
| Name = carnitine O-octanoyltransferase
| EC_number = 2.3.1.137
| CAS_number = 39369-19-2
| IUBMB_EC_number = 2/3/1/137
| GO_code = 0008458
| image =
| width =
| caption =
}}
In [[enzymology]], a '''carnitine O-octanoyltransferase''' ({{EC number|2.3.1.137}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:octanoyl-CoA + L-carnitine <math>\rightleftharpoons</math> CoA + L-octanoylcarnitine
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[octanoyl-CoA]] and [[L-carnitine]], whereas its two [[product (chemistry)|products]] are [[coenzyme A|CoA]] and [[L-octanoylcarnitine]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is '''octanoyl-CoA:L-carnitine O-octanoyltransferase'''. Other names in common use include '''medium-chain/long-chain carnitine acyltransferase''', '''carnitine medium-chain acyltransferase''', '''easily solubilized mitochondrial carnitine palmitoyltransferase''', and '''overt mitochondrial carnitine palmitoyltransferase'''.
 
==Structural studies==
 
As of late 2007, 4 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1XL7}}, {{PDB link|1XL8}}, {{PDB link|1XMC}}, and {{PDB link|1XMD}}.
 
==References==
{{reflist|1}}
* {{cite journal | author = Farrell SO, Fiol CJ, Reddy JK, Bieber LL | date = 1984 | title = Properties of purified carnitine acyltransferases of mouse liver peroxisomes | journal = J. Biol. Chem. | volume = 259 | pages = 13089&ndash;95  | pmid = 6436243 | issue = 21 }}
* {{cite journal | author = Healy MJ, Kerner J, Bieber LL | date = 1988 | title = Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase? | journal = Biochem. J. | volume = 249 | pages = 231&ndash;7  | pmid = 3342008 | issue = 1 | pmc = 1148689 }}
* {{cite journal | author = Miyazawa S, Ozasa H, Osumi T, Hashimoto T | date = Tokyo | title = Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver | journal = J. | volume = Biochem. | pages = 529&ndash;42  | pmid = 6630173 | issue = 2 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:Enzymes of known structure]]

Latest revision as of 21:46, 17 March 2013

Template:Enzyme In enzymology, a carnitine O-octanoyltransferase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

octanoyl-CoA + L-carnitine CoA + L-octanoylcarnitine

Thus, the two substrates of this enzyme are octanoyl-CoA and L-carnitine, whereas its two products are CoA and L-octanoylcarnitine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is octanoyl-CoA:L-carnitine O-octanoyltransferase. Other names in common use include medium-chain/long-chain carnitine acyltransferase, carnitine medium-chain acyltransferase, easily solubilized mitochondrial carnitine palmitoyltransferase, and overt mitochondrial carnitine palmitoyltransferase.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

43 year old Petroleum Engineer Harry from Deep River, usually spends time with hobbies and interests like renting movies, property developers in singapore new condominium and vehicle racing. Constantly enjoys going to destinations like Camino Real de Tierra Adentro.

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    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

    The data offered is for normal info purposes only and isn't supposed to be personalised investment or monetary advice. Motley Fool Singapore contributor Stanley Lim would not personal shares in any corporations talked about. Singapore private home costs increased by 1.eight% within the fourth quarter of 2012, up from 0.6% within the earlier quarter. Resale prices of government-built HDB residences which are usually bought by Singaporeans, elevated by 2.5%, quarter on quarter, the quickest acquire in five quarters. And industrial property, prices are actually double the levels of three years ago. No withholding tax in the event you sell your property. All your local information regarding vital HDB policies, condominium launches, land growth, commercial property and more

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    A vendor's stamp duty has been launched on industrial property for the primary time, at rates ranging from 5 per cent to 15 per cent. The Authorities might be trying to reassure the market that they aren't in opposition to foreigners and PRs investing in Singapore's property market. They imposed these measures because of extenuating components available in the market." The sale of new dual-key EC models will even be restricted to multi-generational households only. The models have two separate entrances, permitting grandparents, for example, to dwell separately. The vendor's stamp obligation takes effect right this moment and applies to industrial property and plots which might be offered inside three years of the date of buy. JLL named Best Performing Property Brand for second year running

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