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{{enzyme
| Name = amylosucrase
| EC_number = 2.4.1.4
| CAS_number = 9032-11-5
| IUBMB_EC_number = 2/4/1/4
| GO_code = 0047669
| image =
| width =
| caption =
}}
In [[enzymology]], an '''amylosucrase''' ({{EC number|2.4.1.4}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:sucrose + (1,4-alpha-D-glucosyl)n <math>\rightleftharpoons</math> D-fructose + (1,4-alpha-D-glucosyl)n<sup>+</sup>1
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[sucrose]] and [[(1,4-alpha-D-glucosyl)n]], whereas its two [[product (chemistry)|products]] are [[D-fructose]] and [[(1,4-alpha-D-glucosyl)n+1]].
 
This enzyme belongs to the family of [[glycosyltransferase]]s, specifically the hexosyltransferases. The systematic name of this enzyme class is '''sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase'''. Other names in common use include '''sucrose-glucan glucosyltransferase''', and '''sucrose-1,4-alpha-glucan glucosyltransferase'''. This enzyme participates in [[starch and sucrose metabolism]].
 
==Structural studies==
 
As of late 2007, 10 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|1G5A}}, {{PDB link|1JG9}}, {{PDB link|1JGI}}, {{PDB link|1MVY}}, {{PDB link|1MW0}}, {{PDB link|1MW1}}, {{PDB link|1MW2}}, {{PDB link|1MW3}}, {{PDB link|1S46}}, and {{PDB link|1ZS2}}.
 
==References==
{{reflist|1}}
* {{cite journal | author = AVIGAD G, FEINGOLD DS, HESTRIN S | date = 1957 | title = Enzymatic synthesis and reactions of a sucrose isomer alpha-D-galactopyranosyl-beta-D-fructofuranoside | journal = J. Biol. Chem. | volume = 224 | pages = 295&ndash;307  | pmid = 13398406 | issue = 1 }}
* {{cite journal | author = Hehre EJ | date = 1951 | title = Enzymic synthesis of polysaccharides: a biological type of polymerization | journal = Adv. Enzymol. Relat. Subj. Biochem. | volume = 11 | pages = 297&ndash;337 | doi = 10.1002/9780470122563.ch6 | series = Advances in Enzymology - and Related Areas of Molecular Biology | isbn = 978-0-470-12256-3 }}
* {{cite journal | author = Hehre EJ, Hamilton DM and Carlson AS | date = 1949 | title = Synthesis of a polsaccharide of the starch glycogen class from sucrose by a cell-free, bacterial enzyme system (amylosucrase) | journal = J. Biol. Chem. | volume = 177 | pages = 267&ndash;279 }}
 
{{enzyme-stub}}
 
[[Category:EC 2.4.1]]
[[Category:Enzymes of known structure]]

Revision as of 03:14, 7 January 2014

Template:Enzyme In enzymology, an amylosucrase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

sucrose + (1,4-alpha-D-glucosyl)n D-fructose + (1,4-alpha-D-glucosyl)n+1

Thus, the two substrates of this enzyme are sucrose and (1,4-alpha-D-glucosyl)n, whereas its two products are D-fructose and (1,4-alpha-D-glucosyl)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase. Other names in common use include sucrose-glucan glucosyltransferase, and sucrose-1,4-alpha-glucan glucosyltransferase. This enzyme participates in starch and sucrose metabolism.

Structural studies

As of late 2007, 10 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, Template:PDB link, and Template:PDB link.

References

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Template:Enzyme-stub