Alcohol oxidase: Difference between revisions

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Removed comments on methane metabolism. Alcohol oxidase is not part of that pathway, it is a dehydrogenase.
 
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{{enzyme
| Name = D-2-hydroxy-acid dehydrogenase
| EC_number = 1.1.99.6
| CAS_number = 9028-83-5
| IUBMB_EC_number = 1/1/99/6
| GO_code = 0047809
| image = 
| width =
| caption =
}}
In [[enzymology]], a '''D-2-hydroxy-acid dehydrogenase''' ({{EC number|1.1.99.6}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


:(R)-lactate + acceptor <math>\rightleftharpoons</math> pyruvate + reduced acceptor


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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[(R)-lactate]] and [[Electron acceptor|acceptor]], whereas its two [[product (chemistry)|products]] are [[pyruvate]] and [[reduced acceptor]].
 
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is '''(R)-2-hydroxy-acid:acceptor 2-oxidoreductase'''. Other names in common use include '''D-2-hydroxy acid dehydrogenase''', and '''(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase'''. It has 2 [[cofactor (biochemistry)|cofactors]]: [[FAD]], and [[Zinc]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Gregolin C, Singer TP, Kearney EB, Boeri E | year = 1961 | title = The formation and enzymatic properties of the various lactic dehydrogenases of yeast | journal = Ann. N. Y. Acad. Sci. | volume = 94 | issue = 3 | pages = 780&ndash;97 | pmid = 13901630 | doi = 10.1111/j.1749-6632.1961.tb35573.x }}
* {{cite journal | author = Nygaard AP | year = 1961 | title = D(-)-Lactate cytochrome c reductase, a flavoprotein from yeast | journal = J. Biol. Chem. | volume = 236 | pages = 920&ndash;925 }}
* {{cite journal | author = Tubbs PK and Greville GD | year = 1959 | title = Dehydrogenation of D-lactate by a soluble enzyme from kidney mitochondria | journal = Biochim. Biophys. Acta | volume = 34 | pages = 290&ndash;291 | doi = 10.1016/0006-3002(59)90276-8 | pmid=13839714}}
 
[[Category:EC 1.1.99]]
[[Category:Flavin enzymes]]
[[Category:Zinc enzymes]]
[[Category:Enzymes of unknown structure]]
[[Category:Protein families]]
 
 
{{1.1-enzyme-stub}}

Latest revision as of 02:50, 2 March 2013

Template:Enzyme In enzymology, a D-2-hydroxy-acid dehydrogenase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

(R)-lactate + acceptor pyruvate + reduced acceptor

Thus, the two substrates of this enzyme are (R)-lactate and acceptor, whereas its two products are pyruvate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (R)-2-hydroxy-acid:acceptor 2-oxidoreductase. Other names in common use include D-2-hydroxy acid dehydrogenase, and (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase. It has 2 cofactors: FAD, and Zinc.

References

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