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{{enzyme
| Name = dolichyl-phosphatase
| EC_number = 3.1.3.51
| CAS_number = 72994-50-4
| IUBMB_EC_number = 3/1/3/51
| GO_code = 0047873
| image =
| width =
| caption =
}}
In [[enzymology]], a '''dolichyl-phosphatase''' ({{EC number|3.1.3.51}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:dolichyl phosphate + H<sub>2</sub>O <math>\rightleftharpoons</math> dolichol + phosphate


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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[dolichyl phosphate]] and [[water|H<sub>2</sub>O]], whereas its two [[product (chemistry)|products]] are [[dolichol]] and [[phosphate]].
 
This enzyme belongs to the family of [[hydrolase]]s, to be specific, those acting on phosphoric [[ester|monoester]] bondsThe systematic name of this enzyme class is '''dolichyl-phosphate phosphohydrolase'''. Other names in common use include '''dolichol phosphate phosphatase''', '''dolichol phosphatase''', '''dolichol monophosphatase''', '''dolichyl monophosphate phosphatase''', '''dolichyl phosphate phosphatase''', '''polyisoprenyl phosphate phosphatase''', '''polyprenylphosphate phosphatase''', and '''Dol-P phosphatase'''. This enzyme participates in [[n-glycan biosynthesis]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Adrian GS, Keenan RW | date = 1979 | title = A dolichyl phosphate-cleaving acid phosphatase from Tetrahymena pyriformis | journal = Biochim. Biophys. Acta. | volume = 575 | pages = 431&ndash;8  | pmid = 229909 | issue = 3 }}
* {{cite journal | author = Rip JW, Rupar CA, Chaudhary N, Carroll KK | date = 1981 | title = Localization of a dolichyl phosphate phosphatase in plasma membranes of rat liver | journal = J. Biol. Chem. | volume = 256 | pages = 1929&ndash;34  | pmid = 6257694 | issue = 4 }}
* {{cite journal | author = Wedgwood JF, Strominger JL | date = 1980 | title = Enzymatic activities in cultured human lymphocytes that dephosphorylate dolichyl pyrophosphate and dolichyl phosphate | journal = J. Biol. Chem. | volume = 255 | pages = 1120&ndash;3  | pmid = 6243292 | issue = 3 }}
 
{{hydrolase-stub}}
 
[[Category:EC 3.1.3]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 20:33, 17 November 2012

Template:Enzyme In enzymology, a dolichyl-phosphatase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

dolichyl phosphate + H2O dolichol + phosphate

Thus, the two substrates of this enzyme are dolichyl phosphate and H2O, whereas its two products are dolichol and phosphate.

This enzyme belongs to the family of hydrolases, to be specific, those acting on phosphoric monoester bonds. The systematic name of this enzyme class is dolichyl-phosphate phosphohydrolase. Other names in common use include dolichol phosphate phosphatase, dolichol phosphatase, dolichol monophosphatase, dolichyl monophosphate phosphatase, dolichyl phosphate phosphatase, polyisoprenyl phosphate phosphatase, polyprenylphosphate phosphatase, and Dol-P phosphatase. This enzyme participates in n-glycan biosynthesis.

References

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