Citrullinase

Template:Enzyme Template:Lowercase In enzymology, a dCTP deaminase (dUMP-forming) (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

dCTP + 2 H₂O $\rightleftharpoons$ dUMP + diphosphate + NH₃

Thus, the two substrates of this enzyme are dCTP and H₂O, whereas its 3 products are dUMP, diphosphate, and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is dCTP aminohydrolase (dUMP-forming). This enzyme participates in pyrimidine metabolism.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Template:PDB link, Template:PDB link, and Template:PDB link.

References

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