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{{enzyme
| Name = aminoglycoside N3'-acetyltransferase
| EC_number = 2.3.1.81
| CAS_number = 60120-42-5
| IUBMB_EC_number = 2/3/1/81
| GO_code = 0046353
| image =
| width =
| caption =
}}
In [[enzymology]], an '''aminoglycoside N3'-acetyltransferase''' ({{EC number|2.3.1.81}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:acetyl-CoA + a 2-deoxystreptamine antibiotic <math>\rightleftharpoons</math> CoA + N<sub>3</sub>'-acetyl-2-deoxystreptamine antibiotic
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[acetyl-CoA]] and [[2-deoxystreptamine antibiotic]], whereas its two [[product (chemistry)|products]] are [[coenzyme A|CoA]] and [[N3'-acetyl-2-deoxystreptamine antibiotic]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is '''acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase'''. Other names in common use include '''3'-aminoglycoside acetyltransferase''', and '''3-N-aminoglycoside acetyltransferase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Davies J, O'Connor S | date = 1978 | title = Enzymatic modification of aminoglycoside antibiotics: 3-N-acetyltransferase with broad specificity that determines resistance to the novel aminoglycoside apramycin | journal = Antimicrob. Agents. Chemother. | volume = 14 | pages = 69&ndash;72  | pmid = 356726 | issue = 1 | pmc = 352406 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]

Revision as of 22:45, 16 September 2012

Template:Enzyme In enzymology, an aminoglycoside N3'-acetyltransferase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + a 2-deoxystreptamine antibiotic CoA + N3'-acetyl-2-deoxystreptamine antibiotic

Thus, the two substrates of this enzyme are acetyl-CoA and 2-deoxystreptamine antibiotic, whereas its two products are CoA and N3'-acetyl-2-deoxystreptamine antibiotic.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase. Other names in common use include 3'-aminoglycoside acetyltransferase, and 3-N-aminoglycoside acetyltransferase.

References

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