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| Name = N-acetylneuraminate 7-O(or 9-O)-acetyltransferase
| EC_number = 2.3.1.45
| CAS_number = 9054-50-6
| IUBMB_EC_number = 2/3/1/45
| GO_code = 0047186
| image =
| width =
| caption =
}}
In [[enzymology]], a '''N-acetylneuraminate 7-O(or 9-O)-acetyltransferase''' ({{EC number|2.3.1.45}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:acetyl-CoA + N-acetylneuraminate <math>\rightleftharpoons</math> CoA + N-acetyl-7-O(or 9-O)-acetylneuraminate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[acetyl-CoA]] and [[N-acetylneuraminate]], whereas its 3 [[product (chemistry)|products]] are [[coenzyme A|CoA]], [[N-acetyl-7-O-acetylneuraminate]], and [[N-acetyl-9-O-acetylneuraminate]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups.  The systematic name of this enzyme class is '''acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase'''. Other names in common use include '''N-acetylneuraminate 7(8)-O-acetyltransferase''', '''sialate O-acetyltransferase''', '''N-acetylneuraminate 7,8-O-acetyltransferase''', '''acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase''', '''acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase''', '''glycoprotein 7(9)-O-acetyltransferase''', '''acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase''', '''N-acetylneuraminate O7-(or O9-)acetyltransferase''', and '''acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase'''.
 
==References==
{{reflist|1}}
* {{cite journal | author = Schauer R | date = 1970 | title = [Biosynthesis of N-acetyl-O-acetylneuraminic acids. I. Incorporation of (14C) acetate into sections of the submaxillary salivary gland of ox and horse] | journal = Hoppe. Seylers. Z. Physiol. Chem. | volume = 351 | pages = 595&ndash;602  | pmid = 5446640 | issue = 5 }}
* {{cite journal | doi = 10.1515/bchm2.1970.351.1.749 | author = Schauer R | date = 1970 | title = [Biosynthesis of N-acetyl-O-acetylneuraminic acids. II. Substrate and intracellular localization of bovine acetyl-coenzyme A: N-acetylneuraminate-7- and 8-O-acetyltransferase] | journal = Hoppe. Seylers. Z. Physiol. Chem. | volume = 351 | pages = 749&ndash;58  | pmid = 5425947 | issue = 6 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:Enzymes of unknown structure]]

Latest revision as of 21:48, 17 March 2013

Template:Enzyme In enzymology, a N-acetylneuraminate 7-O(or 9-O)-acetyltransferase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + N-acetylneuraminate CoA + N-acetyl-7-O(or 9-O)-acetylneuraminate

Thus, the two substrates of this enzyme are acetyl-CoA and N-acetylneuraminate, whereas its 3 products are CoA, N-acetyl-7-O-acetylneuraminate, and N-acetyl-9-O-acetylneuraminate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase. Other names in common use include N-acetylneuraminate 7(8)-O-acetyltransferase, sialate O-acetyltransferase, N-acetylneuraminate 7,8-O-acetyltransferase, acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase, acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase, glycoprotein 7(9)-O-acetyltransferase, acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase, N-acetylneuraminate O7-(or O9-)acetyltransferase, and acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase.

References

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