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{{enzyme
| Name = N-hydroxyarylamine O-acetyltransferase
| EC_number = 2.3.1.118
| CAS_number = 100984-92-7
| IUBMB_EC_number = 2/3/1/118
| GO_code = 0046990
| image =
| width =  
| caption =  
}}
In [[enzymology]], a '''N-hydroxyarylamine O-acetyltransferase''' ({{EC number|2.3.1.118}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
 
:acetyl-CoA + an N-hydroxyarylamine <math>\rightleftharpoons</math> CoA + an N-acetoxyarylamine
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[acetyl-CoA]] and [[N-hydroxyarylamine]], whereas its two [[product (chemistry)|products]] are [[coenzyme A|CoA]] and [[N-acetoxyarylamine]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those [[acyltransferase]]s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is '''acetyl-CoA:N-hydroxyarylamine O-acetyltransferase'''. Other names in common use include '''arylhydroxamate N,O-acetyltransferase''', '''arylamine N-acetyltransferase''', and '''N-hydroxy-2-aminofluorene-O-acetyltransferase'''.
 
==Structural studies==
 
As of late 2007, only one [[tertiary structure|structure]] has been solved for this class of enzymes, with the [[Protein Data Bank|PDB]] accession code {{PDB link|1E2T}}.
 
==References==
{{reflist|1}}
* {{cite journal | author = Saito K, Shinohara A, Kamataki T, Kato R | date = Tokyo | title = N-hydroxyarylamine O-acetyltransferase in hamster liver: identity with arylhydroxamic acid N,O-acetyltransferase and arylamine N-acetyltransferase | journal = J. | volume = Biochem. | pages = 1689&ndash;97  | pmid = 3745141 | issue = 6 }}
 
{{transferase-stub}}
 
[[Category:EC 2.3.1]]
[[Category:Enzymes of known structure]]

Revision as of 21:48, 17 March 2013

Template:Enzyme In enzymology, a N-hydroxyarylamine O-acetyltransferase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + an N-hydroxyarylamine CoA + an N-acetoxyarylamine

Thus, the two substrates of this enzyme are acetyl-CoA and N-hydroxyarylamine, whereas its two products are CoA and N-acetoxyarylamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N-hydroxyarylamine O-acetyltransferase. Other names in common use include arylhydroxamate N,O-acetyltransferase, arylamine N-acetyltransferase, and N-hydroxy-2-aminofluorene-O-acetyltransferase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Template:PDB link.

References

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