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{{enzyme
| Name = CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
| EC_number = 2.7.8.5
| CAS_number = 9068-49-9
| IUBMB_EC_number = 2/7/8/5
| GO_code = 0008444
| image =
| width =
| caption =
}}
In [[enzymology]], a '''CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase''' ({{EC number|2.7.8.5}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]


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:CDP-diacylglycerol + sn-glycerol 3-phosphate <math>\rightleftharpoons</math> CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate
 
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[CDP-diacylglycerol]] and [[sn-glycerol 3-phosphate]], whereas its two [[product (chemistry)|products]] are [[cytidine monophosphate|CMP]] and [[3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate]].
 
This enzyme belongs to the family of [[transferase]]s, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is '''CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase'''. Other names in common use include '''glycerophosphate phosphatidyltransferase''', '''3-phosphatidyl-1'-glycerol-3'-phosphate synthase''', '''CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase''', '''cytidine 5'-diphospho-1,2-diacyl-sn-glycerol''', '''(CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase''', '''phosphatidylglycerophosphate synthase''', '''phosphatidylglycerolphosphate synthase''', '''PGP synthase''', '''CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase''', '''CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase''', '''glycerol phosphate phosphatidyltransferase''', '''glycerol 3-phosphate phosphatidyltransferase''', '''phosphatidylglycerol phosphate synthase''', '''phosphatidylglycerol phosphate synthetase''', '''phosphatidylglycerophosphate synthetase''', and '''sn-glycerol-3-phosphate phosphatidyltransferase'''. This enzyme participates in [[glycerophospholipid metabolism]].
 
==References==
{{reflist|1}}
* {{cite journal | author = Bleasdale JE, Johnston JM | year = 1982 | title = CMP-dependent incorporation of [14C]Glycerol 3-phosphate into phosphatidylglycerol and phosphatidylglycerol phosphate by rabbit lung microsomes | journal = Biochim. Biophys. Acta. | volume = 710 | pages = 377&ndash;90  | pmid = 7074121 | issue = 3 }}
* {{cite journal | author = Hirabayashi T, Larson TJ, Dowhan W | year = 1976 | title = Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: purification by substrate affinity chromatography on cytidine 5'-diphospho-1,2-diacyl-sn-glycerol sepharose | journal = Biochemistry| volume = 15 | pages = 5205&ndash;11  | pmid = 793612 | doi = 10.1021/bi00669a002 | issue = 24 }}
 
{{DEFAULTSORT:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase}}
[[Category:EC 2.7.8]]
[[Category:Enzymes of unknown structure]]
 
 
{{enzyme-stub}}

Revision as of 08:13, 20 August 2013

Template:Enzyme In enzymology, a CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase (Air Transportation Experts Kull from Wingham, has many interests that include butterflies, property developers in singapore and digital photography. Is a travel freak and in recent past made buy a house in singapore journey to Paleochristian and Byzantine Monuments of Thessalonika.) is an enzyme that catalyzes the chemical reaction

CDP-diacylglycerol + sn-glycerol 3-phosphate CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate

Thus, the two substrates of this enzyme are CDP-diacylglycerol and sn-glycerol 3-phosphate, whereas its two products are CMP and 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase. Other names in common use include glycerophosphate phosphatidyltransferase, 3-phosphatidyl-1'-glycerol-3'-phosphate synthase, CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase, cytidine 5'-diphospho-1,2-diacyl-sn-glycerol, (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase, phosphatidylglycerophosphate synthase, phosphatidylglycerolphosphate synthase, PGP synthase, CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase, CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase, glycerol phosphate phosphatidyltransferase, glycerol 3-phosphate phosphatidyltransferase, phosphatidylglycerol phosphate synthase, phosphatidylglycerol phosphate synthetase, phosphatidylglycerophosphate synthetase, and sn-glycerol-3-phosphate phosphatidyltransferase. This enzyme participates in glycerophospholipid metabolism.

References

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